Format

Send to:

Choose Destination

RPS11 ribosomal protein S11 [ Homo sapiens (human) ]

Gene ID: 6205, updated on 5-Aug-2018

Summary

Official Symbol
RPS11provided by HGNC
Official Full Name
ribosomal protein S11provided by HGNC
Primary source
HGNC:HGNC:10384
See related
Ensembl:ENSG00000142534 MIM:180471; Vega:OTTHUMG00000183156
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
S11
Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the S17P family of ribosomal proteins that is a component of the 40S subunit. This gene is co-transcribed with the small nucleolar RNA gene U35B, which is located in the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012]
Expression
Ubiquitous expression in ovary (RPKM 1700.9), bone marrow (RPKM 1027.8) and 25 other tissues See more
Orthologs

Genomic context

See RPS11 in Genome Data Viewer
Location:
19q13.33
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 19 NC_000019.10 (49496365..49499712)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (49999622..50002969)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ribosomal protein L13a Neighboring gene small nucleolar RNA, C/D box 34 Neighboring gene small nucleolar RNA, C/D box 35A Neighboring gene small nucleolar RNA, C/D box 35B Neighboring gene microRNA 150 Neighboring gene cytochrome c oxidase subunit 6C pseudogene 7

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Phenotypes

NHGRI GWAS Catalog

Description
Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
NHGRI GWA Catalog
Genome-wide association study of hematological and biochemical traits in a Japanese population.
NHGRI GWA Catalog
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
NHGRI GWA Catalog

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
rRNA binding IEA
Inferred from Electronic Annotation
more info
 
structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
SRP-dependent cotranslational protein targeting to membrane TAS
Traceable Author Statement
more info
 
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
Traceable Author Statement
more info
 
translation IC
Inferred by Curator
more info
PubMed 
translation NAS
Non-traceable Author Statement
more info
PubMed 
translational initiation TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
40S ribosomal protein S11
Names
small ribosomal subunit protein uS17

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001015.4NP_001006.1  40S ribosomal protein S11

    See identical proteins and their annotated locations for NP_001006.1

    Status: REVIEWED

    Source sequence(s)
    AK311809, BI550467, DA879881
    Consensus CDS
    CCDS12769.1
    UniProtKB/Swiss-Prot
    P62280
    Related
    ENSP00000270625.1, OTTHUMP00000270973, ENST00000270625.6, OTTHUMT00000465288
    Conserved Domains (1) summary
    PTZ00241
    Location:1158
    PTZ00241; 40S ribosomal protein S11; Provisional

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p12 Primary Assembly

    Range
    49496365..49499712
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center