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RPL37A ribosomal protein L37a [ Homo sapiens (human) ]

Gene ID: 6168, updated on 11-Apr-2024


Official Symbol
RPL37Aprovided by HGNC
Official Full Name
ribosomal protein L37aprovided by HGNC
Primary source
See related
Ensembl:ENSG00000197756 MIM:613314; AllianceGenome:HGNC:10348
Gene type
protein coding
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
L37A; eL43
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37AE family of ribosomal proteins. It is located in the cytoplasm. The protein contains a C4-type zinc finger-like domain. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Ubiquitous expression in ovary (RPKM 975.8), fat (RPKM 601.9) and 25 other tissues See more
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Genomic context

See RPL37A in Genome Data Viewer
Exon count:
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (216498844..216504086)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (216981257..216986499)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (217363567..217368809)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene SMARCAL1 antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 13820 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17096 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:217339556-217340056 Neighboring gene RPL37A divergent transcript Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17098 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12305 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17099 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17100 Neighboring gene uncharacterized LOC101928156 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:217390604-217391496 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17101 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:217417655-217418166 Neighboring gene uncharacterized LOC101928180 Neighboring gene uncharacterized LOC105373871 Neighboring gene uncharacterized LOC124907976

Genomic regions, transcripts, and products


  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Pr55(Gag) gag HIV-1 Gag interacts with RPL37A as demonstrated by proximity dependent biotinylation proteomics PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Clone Names

  • FLJ13357, MGC74786

General protein information

Preferred Names
large ribosomal subunit protein eL43
60S ribosomal protein L37a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_000998.5NP_000989.1  large ribosomal subunit protein eL43

    See identical proteins and their annotated locations for NP_000989.1

    Status: REVIEWED

    Source sequence(s)
    AC073321, BC014262, CD249666, L06499
    Consensus CDS
    P12751, P61513, Q6FGF5
    ENSP00000418082.1, ENST00000491306.6
    Conserved Domains (1) summary
    Ribosomal_L37ae; Ribosomal L37ae protein family

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly


  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0


  1. NC_060926.1 Alternate T2T-CHM13v2.0

    GenBank, FASTA, Sequence Viewer (Graphics)