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HMGB4 high mobility group box 4 [ Canis lupus familiaris (dog) ]

Gene ID: 609219, updated on 17-Aug-2024

Summary

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Official Symbol
HMGB4provided by VGNC
Official Full Name
high mobility group box 4provided by VGNC
Primary source
VGNC:VGNC:41711
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See HMGB4 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
1
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (8061106..8061848, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (8158414..8159156, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (7986253..7986995, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (7890761..7891503, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (7970955..7971697, complement)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene CUB and Sushi multiple domains 2 Neighboring gene uncharacterized LOC119867933 Neighboring gene uncharacterized LOC119867932 Neighboring gene chromosome 15 C16orf87 homolog Neighboring gene glutamic--pyruvic transaminase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding, bending IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
high mobility group protein B4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    8061106..8061848 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038687610.1 → XP_038543538.1  high mobility group protein B4

    UniProtKB/TrEMBL
    A0A8C0KDN7, A0A8C0NC19, A0A8C0S1H4
    Conserved Domains (2) summary
    cd00084
    Location:11 → 77
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd01390
    Location:95 → 160
    HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    7890761..7891503 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038495621.1 → XP_038351549.1  high mobility group protein B4

    Conserved Domains (2) summary
    cd00084
    Location:11 → 77
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd01390
    Location:95 → 160
    HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

    Range
    7970955..7971697 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038621847.1 → XP_038477775.1  high mobility group protein B4

    Conserved Domains (2) summary
    cd00084
    Location:11 → 77
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd01390
    Location:95 → 160
    HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

    Range
    7986253..7986995 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038557977.1 → XP_038413905.1  high mobility group protein B4

    UniProtKB/TrEMBL
    A0A8C0KDN7, A0A8C0NC19, A0A8C0S1H4
    Conserved Domains (2) summary
    cd00084
    Location:11 → 77
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd01390
    Location:95 → 160
    HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    8158414..8159156 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_846436.6 → XP_851529.2  high mobility group protein B4

    UniProtKB/TrEMBL
    A0A8C0KDN7, A0A8C0NC19, A0A8C0S1H4
    Conserved Domains (2) summary
    cd00084
    Location:11 → 77
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd01390
    Location:95 → 160
    HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...
Nucleotide Protein
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