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Chst7 carbohydrate sulfotransferase 7 [ Mus musculus (house mouse) ]

Gene ID: 60322, updated on 5-Mar-2024

Summary

Official Symbol
Chst7provided by MGI
Official Full Name
carbohydrate sulfotransferase 7provided by MGI
Primary source
MGI:MGI:1891767
See related
Ensembl:ENSMUSG00000037347 AllianceGenome:MGI:1891767
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
GST5; C6ST-2; Gn6st-4; glcNAc6ST-4; 2600013M07Rik
Summary
Predicted to enable N-acetylglucosamine 6-O-sulfotransferase activity and chondroitin 6-sulfotransferase activity. Predicted to be involved in N-acetylglucosamine metabolic process and chondroitin sulfate biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in trans-Golgi network. Is expressed in several structures, including brain; heart; liver; lung; and tail unsegmented mesenchyme. Orthologous to human CHST7 (carbohydrate sulfotransferase 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in lung adult (RPKM 3.9), ovary adult (RPKM 3.0) and 27 other tissues See more
Orthologs
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Genomic context

Location:
X A1.3; X 15.5 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (19925202..19965361)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (20058963..20099991)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene ribosomal protein L36, pseudogene 10 Neighboring gene STARR-seq mESC enhancer starr_46872 Neighboring gene STARR-seq mESC enhancer starr_46873 Neighboring gene predicted gene 5384 Neighboring gene STARR-seq mESC enhancer starr_46874 Neighboring gene solute carrier family 9 (sodium/hydrogen exchanger), member 7 Neighboring gene 40S ribosomal protein SA pseudogene Neighboring gene STARR-seq mESC enhancer starr_46875 Neighboring gene STARR-positive B cell enhancer ABC_E11046 Neighboring gene transcription initiation factor IIA subunit 1-like Neighboring gene retinitis pigmentosa 2 homolog

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables N-acetylglucosamine 6-O-sulfotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables N-acetylglucosamine 6-O-sulfotransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables chondroitin 6-sulfotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables chondroitin 6-sulfotransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables chondroitin 6-sulfotransferase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables sulfotransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in N-acetylglucosamine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in N-acetylglucosamine metabolic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in chondroitin sulfate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in chondroitin sulfate biosynthetic process ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in sulfur compound metabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
carbohydrate sulfotransferase 7
Names
N-acetylglucosamine 6-O-sulfotransferase 1
N-acetylglucosamine 6-O-sulfotransferase 4
carbohydrate (N-acetylglucosamino) sulfotransferase 7
chondroitin 6-sulfotransferase 2
galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5
NP_068361.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021715.1NP_068361.1  carbohydrate sulfotransferase 7 precursor

    See identical proteins and their annotated locations for NP_068361.1

    Status: VALIDATED

    Source sequence(s)
    AB040710
    Consensus CDS
    CCDS30040.1
    UniProtKB/Swiss-Prot
    Q99NB0, Q9EP78
    Related
    ENSMUSP00000043222.8, ENSMUST00000044138.8

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    19925202..19965361
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_878032.4 RNA Sequence