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Ndufs5 NADH:ubiquinone oxidoreductase core subunit S5 [ Mus musculus (house mouse) ]

Gene ID: 595136, updated on 30-Apr-2024

Summary

Official Symbol
Ndufs5provided by MGI
Official Full Name
NADH:ubiquinone oxidoreductase core subunit S5provided by MGI
Primary source
MGI:MGI:1890889
See related
Ensembl:ENSMUSG00000028648 AllianceGenome:MGI:1890889
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Is expressed in several structures, including alimentary system; ear; genitourinary system; integumental system; and nervous system. Orthologous to human NDUFS5 (NADH:ubiquinone oxidoreductase subunit S5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in cerebellum adult (RPKM 103.8), CNS E18 (RPKM 84.0) and 23 other tissues See more
Orthologs
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Genomic context

See Ndufs5 in Genome Data Viewer
Location:
4 D2.2; 4 57.42 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (123606503..123611979, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (123712710..123718186, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene microtubule-actin crosslinking factor 1 Neighboring gene STARR-seq mESC enhancer starr_11311 Neighboring gene predicted gene 12925 Neighboring gene STARR-positive B cell enhancer ABC_E2119 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E6212 Neighboring gene STARR-positive B cell enhancer ABC_E1654 Neighboring gene predicted gene, 57730 Neighboring gene akirin 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5
Names
CI-15 kDa
NADH dehydrogenase (ubiquinone) Fe-S protein 5
NADH-ubiquinone oxidoreductase 15 kDa subunit
complex I-15 kDa
NP_001025445.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030274.1NP_001025445.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

    See identical proteins and their annotated locations for NP_001025445.1

    Status: VALIDATED

    Source sequence(s)
    BC081434, BU534760
    Consensus CDS
    CCDS18618.1
    UniProtKB/Swiss-Prot
    Q3U734, Q99LY9
    UniProtKB/TrEMBL
    B1ARW4
    Related
    ENSMUSP00000030401.8, ENSMUST00000030401.14
    Conserved Domains (1) summary
    pfam10200
    Location:296
    Ndufs5; NADH:ubiquinone oxidoreductase, NDUFS5-15kDa

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    123606503..123611979 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)