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Golga7 golgin A7 [ Mus musculus (house mouse) ]

Gene ID: 57437, updated on 2-Nov-2024

Summary

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Official Symbol
Golga7provided by MGI
Official Full Name
golgin A7provided by MGI
Primary source
MGI:MGI:1931029
See related
Ensembl:ENSMUSG00000015341 AllianceGenome:MGI:1931029
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
GCP16; HSPC041; GOLGA3AP1; C130038N16Rik
Summary
Predicted to be involved in establishment of protein localization to membrane; peptidyl-L-cysteine S-palmitoylation; and protein stabilization. Predicted to act upstream of or within Golgi to plasma membrane transport. Predicted to be located in Golgi membrane. Predicted to be part of palmitoyltransferase complex. Predicted to be active in Golgi stack. Is expressed in several structures, including alimentary system; eye; genitourinary system; integumental system; and nervous system. Orthologous to human GOLGA7 (golgin A7). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in CNS E14 (RPKM 35.4), limb E14.5 (RPKM 33.1) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Golga7 in Genome Data Viewer
Location:
8 A2; 8 11.42 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (23731342..23747096, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (23241326..23258903, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30247 Neighboring gene glycerol-3-phosphate acyltransferase 4 Neighboring gene STARR-positive B cell enhancer ABC_E10494 Neighboring gene STARR-positive B cell enhancer ABC_E356 Neighboring gene GINS complex subunit 4 Neighboring gene predicted gene, 39141 Neighboring gene predicted gene, 24335 Neighboring gene predicted gene, 53407

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras. Wang T, et al. Cell, 2017 Feb 23. PMID 28162770, Free PMC Article
  2. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Gene trapped (1) 
  • Targeted (2) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC30271, MGC102434, MGC118465

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in Golgi to plasma membrane protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in Golgi to plasma membrane protein transport ISO
Inferred from Sequence Orthology
more info
  
involved_in Golgi to plasma membrane protein transport ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within Golgi to plasma membrane transport ISO
Inferred from Sequence Orthology
more info
  
involved_in peptidyl-L-cysteine S-palmitoylation ISO
Inferred from Sequence Orthology
more info
  
involved_in peptidyl-L-cysteine S-palmitoylation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in protein stabilization ISO
Inferred from Sequence Orthology
more info
  
involved_in protein stabilization ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in protein targeting to membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
  
located_in Golgi membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in Golgi stack IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi stack ISO
Inferred from Sequence Orthology
more info
  
located_in Golgi stack ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of palmitoyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of palmitoyltransferase complex ISO
Inferred from Sequence Orthology
more info
  
part_of palmitoyltransferase complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
golgin subfamily A member 7
Names
golgi autoantigen, golgin subfamily a, 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042484.1 → NP_001035949.1  golgin subfamily A member 7

    See identical proteins and their annotated locations for NP_001035949.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC126038, AK150696, BY330336
    Consensus CDS
    CCDS40297.1
    UniProtKB/Swiss-Prot
    Q8BN18, Q91W53, Q9JJE0
    Related
    ENSMUSP00000062983.7, ENSMUST00000051094.9
    Conserved Domains (1) summary
    pfam10256
    Location:12 → 124
    Erf4; Golgin subfamily A member 7/ERF4 family

  2. NM_020585.2 → NP_065610.2  golgin subfamily A member 7

    See identical proteins and their annotated locations for NP_065610.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC126038, AK150696, BY330336
    Consensus CDS
    CCDS40297.1
    UniProtKB/Swiss-Prot
    Q8BN18, Q91W53, Q9JJE0
    Related
    ENSMUSP00000112935.2, ENSMUST00000121783.7
    Conserved Domains (1) summary
    pfam10256
    Location:12 → 124
    Erf4; Golgin subfamily A member 7/ERF4 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    23731342..23747096 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006509179.5 → XP_006509242.1  golgin subfamily A member 7 isoform X1

    See identical proteins and their annotated locations for XP_006509242.1

    Conserved Domains (1) summary
    pfam10256
    Location:12 → 123
    Erf4; Golgin subfamily A member 7/ERF4 family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q91W53.1 GenPept UniProtKB/Swiss-Prot:Q91W53

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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