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Plin4 perilipin 4 [ Mus musculus (house mouse) ]

Gene ID: 57435, updated on 8-May-2024

Summary

Official Symbol
Plin4provided by MGI
Official Full Name
perilipin 4provided by MGI
Primary source
MGI:MGI:1929709
See related
Ensembl:ENSMUSG00000002831 AllianceGenome:MGI:1929709
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
S3-12; mKIAA1881
Summary
Located in plasma membrane. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; immune system; and nervous system. Orthologous to human PLIN4 (perilipin 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in subcutaneous fat pad adult (RPKM 471.2), genital fat pad adult (RPKM 371.8) and 5 other tissues See more
Orthologs
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Genomic context

See Plin4 in Genome Data Viewer
Location:
17 29.16 cM; 17 D
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (56407587..56416947, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (56100587..56109948, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene chromatin assembly factor 1, subunit A Neighboring gene UBX domain protein 6 Neighboring gene STARR-positive B cell enhancer ABC_E100 Neighboring gene HDGF like 2 Neighboring gene nuclear encoded tRNA glutamic acid 4 (anticodon CTC) Neighboring gene perilipin 5 Neighboring gene leucine-rich alpha-2-glycoprotein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (3)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in lipid droplet ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
perilipin-4
Names
adipocyte protein S3-12
plasma membrane associated protein, S3-12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001372234.1NP_001359163.1  perilipin-4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    CT009719
    Consensus CDS
    CCDS89124.1
    UniProtKB/TrEMBL
    A0A571BEC9
    Related
    ENSMUSP00000158677.2, ENSMUST00000238734.2
    Conserved Domains (2) summary
    cl28536
    Location:7821316
    COG5412; Phage-related protein [Mobilome: prophages, transposons]
    pfam03036
    Location:13511582
    Perilipin; Perilipin family
  2. NM_001410163.1NP_001397092.1  perilipin-4 isoform 3

    Status: VALIDATED

    Source sequence(s)
    CT009719
  3. NM_001410164.1NP_001397093.1  perilipin-4 isoform 4

    Status: VALIDATED

    Source sequence(s)
    CT009719
  4. NM_001410165.1NP_001397094.1  perilipin-4 isoform 5

    Status: VALIDATED

    Source sequence(s)
    CT009719
  5. NM_001410166.1NP_001397095.1  perilipin-4 isoform 6

    Status: VALIDATED

    Source sequence(s)
    CT009719
  6. NM_001410167.1NP_001397096.1  perilipin-4 isoform 7

    Status: VALIDATED

    Source sequence(s)
    CT009719
  7. NM_001410168.1NP_001397097.1  perilipin-4 isoform 8

    Status: VALIDATED

    Source sequence(s)
    CT009719
  8. NM_001410172.1NP_001397101.1  perilipin-4 isoform 9

    Status: VALIDATED

    Source sequence(s)
    CT009719
  9. NM_001410173.1NP_001397102.1  perilipin-4 isoform 11

    Status: VALIDATED

    Source sequence(s)
    CT009719
  10. NM_001410174.1NP_001397103.1  perilipin-4 isoform 11

    Status: VALIDATED

    Source sequence(s)
    CT009719
  11. NM_001410175.1NP_001397104.1  perilipin-4 isoform 10

    Status: VALIDATED

    Source sequence(s)
    CT009719
  12. NM_020568.4NP_065593.2  perilipin-4 isoform 2

    See identical proteins and their annotated locations for NP_065593.2

    Status: VALIDATED

    Source sequence(s)
    CT009719
    Consensus CDS
    CCDS79565.1
    UniProtKB/Swiss-Prot
    E9QN72, O88492, Q69Z80, Q8BNV5
    Related
    ENSMUSP00000139859.2, ENSMUST00000190703.7
    Conserved Domains (2) summary
    cl28536
    Location:5841118
    COG5412; Phage-related protein [Mobilome: prophages, transposons]
    pfam03036
    Location:11531384
    Perilipin; Perilipin family

RNA

  1. NR_176959.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    CT009719
  2. NR_176960.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    CT009719

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    56407587..56416947 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011246549.4XP_011244851.1  perilipin-4 isoform X5

    See identical proteins and their annotated locations for XP_011244851.1

    Conserved Domains (2) summary
    cl28536
    Location:6931227
    COG5412; Phage-related protein [Mobilome: prophages, transposons]
    pfam03036
    Location:12621519
    Perilipin; Perilipin family
  2. XM_036160710.1XP_036016603.1  perilipin-4 isoform X9

    Conserved Domains (2) summary
    cl28536
    Location:7821316
    COG5412; Phage-related protein [Mobilome: prophages, transposons]
    pfam03036
    Location:13511466
    Perilipin; Perilipin family
  3. XM_011246548.4XP_011244850.1  perilipin-4 isoform X4

    Conserved Domains (2) summary
    cl28536
    Location:118466
    COG5412; Phage-related protein [Mobilome: prophages, transposons]
    pfam03036
    Location:12741531
    Perilipin; Perilipin family
  4. XM_017317591.3XP_017173080.1  perilipin-4 isoform X8

    Conserved Domains (2) summary
    cl28536
    Location:8041338
    COG5412; Phage-related protein [Mobilome: prophages, transposons]
    pfam03036
    Location:13731485
    Perilipin; Perilipin family
  5. XM_011246551.4XP_011244853.1  perilipin-4 isoform X7

    Conserved Domains (2) summary
    cl28536
    Location:8041338
    COG5412; Phage-related protein [Mobilome: prophages, transposons]
    pfam03036
    Location:13731490
    Perilipin; Perilipin family
  6. XM_011246550.3XP_011244852.1  perilipin-4 isoform X5

    See identical proteins and their annotated locations for XP_011244852.1

    Conserved Domains (2) summary
    cl28536
    Location:6931227
    COG5412; Phage-related protein [Mobilome: prophages, transposons]
    pfam03036
    Location:12621519
    Perilipin; Perilipin family

RNA

  1. XR_004939565.1 RNA Sequence

  2. XR_004939564.1 RNA Sequence