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B4galt3 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3 [ Mus musculus (house mouse) ]

Gene ID: 57370, updated on 8-Dec-2022


Official Symbol
B4galt3provided by MGI
Official Full Name
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000052423 AllianceGenome:MGI:1928767
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ESTM6; ESTM26; 9530061M23Rik
Predicted to enable galactosyltransferase activity. Predicted to be involved in galactosylceramide biosynthetic process and glycosylation. Predicted to be located in cytosol. Predicted to be active in Golgi apparatus. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and respiratory system. Orthologous to human B4GALT3 (beta-1,4-galactosyltransferase 3). [provided by Alliance of Genome Resources, Apr 2022]
Ubiquitous expression in duodenum adult (RPKM 38.6), ovary adult (RPKM 29.1) and 28 other tissues See more
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Genomic context

See B4galt3 in Genome Data Viewer
1 H3; 1 79.29 cM
Exon count:
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (171097898..171104468)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (171270328..171276895)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene Fc receptor, IgE, high affinity I, gamma polypeptide Neighboring gene NADH:ubiquinone oxidoreductase core subunit S2 Neighboring gene a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 Neighboring gene protoporphyrinogen oxidase Neighboring gene ubiquitin specific peptidase 21

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Pathways from PubChem

General gene information



Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables N-acetyllactosamine synthase activity IEA
Inferred from Electronic Annotation
more info
enables beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity IEA
Inferred from Electronic Annotation
more info
enables galactosyltransferase activity ISO
Inferred from Sequence Orthology
more info
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
enables transferase activity IEA
Inferred from Electronic Annotation
more info
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
involved_in galactosylceramide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
involved_in galactosylceramide biosynthetic process ISO
Inferred from Sequence Orthology
more info
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
located_in cytosol ISO
Inferred from Sequence Orthology
more info
located_in membrane IEA
Inferred from Electronic Annotation
more info

General protein information

Preferred Names
beta-1,4-galactosyltransferase 3
N-acetyllactosamine synthase
UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3; beta-1,4-galactosyltransferase III; beta4GalT-III; expressed sequence tag mouse EST 6
UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3
beta-1,4-GalTase 3
beta-1,4-galactosyltransferase III
beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase
beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase
nal synthase
neolactotriaosylceramide beta-1,4-galactosyltransferase

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020579.2NP_065604.2  beta-1,4-galactosyltransferase 3

    See identical proteins and their annotated locations for NP_065604.2

    Status: VALIDATED

    Source sequence(s)
    AF142671, BP772898, BU703242, CD363941
    Consensus CDS
    Q91YY2, Q9QY13
    ENSMUSP00000066353.4, ENSMUST00000064272.10
    Conserved Domains (1) summary
    b4GalT; Beta-4-Galactosyltransferase is involved in the formation of the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000067.7 Reference GRCm39 C57BL/6J

    GenBank, FASTA, Sequence Viewer (Graphics)