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SPRYD7 SPRY domain containing 7 [ Homo sapiens (human) ]

Gene ID: 57213, updated on 9-Feb-2020

Summary

Official Symbol
SPRYD7provided by HGNC
Official Full Name
SPRY domain containing 7provided by HGNC
Primary source
HGNC:HGNC:14297
See related
Ensembl:ENSG00000123178 MIM:607866
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CLLD6; C13orf1
Expression
Ubiquitous expression in lung (RPKM 5.0), brain (RPKM 4.9) and 25 other tissues See more
Orthologs

Genomic context

See SPRYD7 in Genome Data Viewer
Location:
13q14.2
Exon count:
6
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 13 NC_000013.11 (49912702..49936501, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (50486842..50510626, complement)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene CTAGE family member 10, pseudogene Neighboring gene RNY4 pseudogene 9 Neighboring gene deleted in lymphocytic leukemia 2 Neighboring gene microRNA 3613 Neighboring gene tripartite motif containing 13 Neighboring gene potassium channel regulator

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
SPRY domain-containing protein 7
Names
CLL deletion region gene 6 protein
chronic lymphocytic leukemia deletion region gene 6 protein
epididymis secretory sperm binding protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127482.2NP_001120954.1  SPRY domain-containing protein 7 isoform 2

    See identical proteins and their annotated locations for NP_001120954.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) omits an in-frame coding exon resulting in a shorter protein isoform (2) compared to isoform 1.
    Source sequence(s)
    AF334405, AK290576, BM684781, DA485722, DN992366
    Consensus CDS
    CCDS45046.1
    UniProtKB/Swiss-Prot
    Q5W111
    Related
    ENSP00000367437.2, ENST00000378195.6
    Conserved Domains (1) summary
    cd12880
    Location:8157
    SPRYD7; SPRY domain-containing protein 7
  2. NM_020456.4NP_065189.1  SPRY domain-containing protein 7 isoform 1

    See identical proteins and their annotated locations for NP_065189.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the predicted full length protein isoform (1).
    Source sequence(s)
    AF055016, AF334405, BC022519, BM684781, DN992366
    Consensus CDS
    CCDS9422.1
    UniProtKB/Swiss-Prot
    Q5W111
    UniProtKB/TrEMBL
    A0A024RDT6
    Related
    ENSP00000354774.3, ENST00000361840.8
    Conserved Domains (1) summary
    cd12880
    Location:35196
    SPRYD7; SPRY domain-containing protein 7

RNA

  1. NR_023351.3 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) omits two coding exons resulting in a frameshift and premature stop codon. The transcript is predicted to be a candidate for nonsense-mediated decay.
    Source sequence(s)
    AF334405, BM684781, DA388141, DN992366

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p13 Primary Assembly

    Range
    49912702..49936501 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017020677.1XP_016876166.1  SPRY domain-containing protein 7 isoform X1

RNA

  1. XR_001749634.1 RNA Sequence

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