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Adrm1 adhesion regulating molecule 1 26S proteasome ubiquitin receptor [ Mus musculus (house mouse) ]

Gene ID: 56436, updated on 8-Feb-2024

Summary

Official Symbol
Adrm1provided by MGI
Official Full Name
adhesion regulating molecule 1 26S proteasome ubiquitin receptorprovided by MGI
Primary source
MGI:MGI:1929289
See related
Ensembl:ENSMUSG00000039041 AllianceGenome:MGI:1929289
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Arm1; ARM-1; Gp110; Rpn13; 1110063P18Rik; 2510006J17Rik
Summary
Predicted to enable several functions, including endopeptidase activator activity; proteasome binding activity; and ubiquitin binding activity. Involved in several processes, including germ cell development; gonad development; and positive regulation of growth hormone receptor signaling pathway. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be part of proteasome regulatory particle, lid subcomplex. Is expressed in genitourinary system; sensory organ; and skeleton. Orthologous to human ADRM1 (ADRM1 26S proteasome ubiquitin receptor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 108.3), duodenum adult (RPKM 65.5) and 28 other tissues See more
Orthologs
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Genomic context

See Adrm1 in Genome Data Viewer
Location:
2 H4; 2 102.69 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (179813381..179818076)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (180171588..180176283)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 46782 Neighboring gene STARR-positive B cell enhancer ABC_E332 Neighboring gene oxysterol binding protein-like 2 Neighboring gene predicted gene, 29886 Neighboring gene STARR-positive B cell enhancer mm9_chr2:179905789-179906089 Neighboring gene microRNA 7005 Neighboring gene laminin, alpha 5 Neighboring gene STARR-seq mESC enhancer starr_06728 Neighboring gene STARR-seq mESC enhancer starr_06729 Neighboring gene STARR-positive B cell enhancer ABC_E6036 Neighboring gene microRNA 3091 Neighboring gene ribosomal protein S21

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (3)  1 citation
  • Endonuclease-mediated (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables endopeptidase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables endopeptidase activator activity ISO
Inferred from Sequence Orthology
more info
 
enables molecular function inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
enables protease binding ISO
Inferred from Sequence Orthology
more info
 
enables proteasome binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables proteasome binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
part_of proteasome complex ISO
Inferred from Sequence Orthology
more info
 
part_of proteasome regulatory particle, lid subcomplex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
proteasomal ubiquitin receptor ADRM1
Names
110 kDa cell membrane glycoprotein
adhesion-regulating molecule 1
glycoprotein 110
rpn13 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019822.3NP_062796.2  proteasomal ubiquitin receptor ADRM1

    See identical proteins and their annotated locations for NP_062796.2

    Status: PROVISIONAL

    Source sequence(s)
    AL663027
    Consensus CDS
    CCDS17171.1
    UniProtKB/Swiss-Prot
    Q3UKZ8, Q8BPH8, Q922A7, Q9JKV1
    UniProtKB/TrEMBL
    A0A0A6YVU8
    Related
    ENSMUSP00000050076.5, ENSMUST00000061437.5
    Conserved Domains (2) summary
    cd13314
    Location:24128
    PH_Rpn13; Pleckstrin homology-like domain of Regulatory Particle Non-ATPase 13
    pfam16550
    Location:274381
    RPN13_C; UCH-binding domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    179813381..179818076
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)