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Dstn destrin [ Mus musculus (house mouse) ]

Gene ID: 56431, updated on 7-Apr-2019

Summary

Official Symbol
Dstnprovided by MGI
Official Full Name
destrinprovided by MGI
Primary source
MGI:MGI:1929270
See related
Ensembl:ENSMUSG00000015932
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ADF; Dsn; corn1; sid23p; AU042046; 2610043P17Rik
Expression
Biased expression in bladder adult (RPKM 498.8), large intestine adult (RPKM 115.0) and 14 other tissues See more
Orthologs

Genomic context

See Dstn in Genome Data Viewer
Location:
2 G1; 2 70.89 cM
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (143915331..143943324)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (143741067..143769060)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene beaded filament structural protein 1, in lens-CP94 Neighboring gene predicted gene, 33648 Neighboring gene 60S ribosomal protein L35a pseudogene Neighboring gene predicted gene, 33804 Neighboring gene ribosome binding protein 1 Neighboring gene barrier to autointegration factor 2 Neighboring gene barrier to autointegration factor 2, opposite strand

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
actin binding IEA
Inferred from Electronic Annotation
more info
 
actin filament binding IDA
Inferred from Direct Assay
more info
PubMed 
actin filament binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
actin filament depolymerization IDA
Inferred from Direct Assay
more info
PubMed 
actin filament depolymerization ISO
Inferred from Sequence Orthology
more info
 
actin filament fragmentation IDA
Inferred from Direct Assay
more info
PubMed 
actin filament severing IEA
Inferred from Electronic Annotation
more info
 
positive regulation of actin filament depolymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
cortical actin cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
destrin
Names
actin-depolymerizing factor
corneal disease 1
sid 23

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019771.2NP_062745.1  destrin

    See identical proteins and their annotated locations for NP_062745.1

    Status: VALIDATED

    Source sequence(s)
    AB025406, BF123977
    Consensus CDS
    CCDS16812.1
    UniProtKB/Swiss-Prot
    Q9R0P5
    UniProtKB/TrEMBL
    Q4FK36
    Related
    ENSMUSP00000099461.3, ENSMUST00000103172.3
    Conserved Domains (1) summary
    cd11286
    Location:3152
    ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

    Range
    143915331..143943324
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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