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Srcin1 SRC kinase signaling inhibitor 1 [ Mus musculus (house mouse) ]

Gene ID: 56013, updated on 2-Nov-2024

Summary

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Official Symbol
Srcin1provided by MGI
Official Full Name
SRC kinase signaling inhibitor 1provided by MGI
Primary source
MGI:MGI:1933179
See related
Ensembl:ENSMUSG00000038453 AllianceGenome:MGI:1933179
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
P140; SNIP; p140Cap; mKIAA1684
Summary
Predicted to enable protein domain specific binding activity and protein kinase binding activity. Involved in regulation of synapse assembly. Acts upstream of or within negative regulation of cell adhesion. Located in postsynaptic density. Is active in glutamatergic synapse and presynapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and respiratory system. Orthologous to human SRCIN1 (SRC kinase signaling inhibitor 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in cerebellum adult (RPKM 19.1), cortex adult (RPKM 17.2) and 10 other tissues See more
Orthologs
human all
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Genomic context

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See Srcin1 in Genome Data Viewer
Location:
11 D; 11 61.0 cM
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (97400166..97466059, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (97509340..97575246, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene suppressor of cytokine signaling 7 Neighboring gene STARR-seq mESC enhancer starr_30603 Neighboring gene STARR-positive B cell enhancer ABC_E10709 Neighboring gene Rho GTPase activating protein 23 Neighboring gene STARR-seq mESC enhancer starr_30610 Neighboring gene RIKEN cDNA 4933428G20 gene Neighboring gene STARR-positive B cell enhancer ABC_E11489 Neighboring gene STARR-positive B cell enhancer ABC_E11490 Neighboring gene STARR-positive B cell enhancer mm9_chr11:97394449-97394749 Neighboring gene STARR-seq mESC enhancer starr_30619 Neighboring gene RIKEN cDNA 2410003L11 gene Neighboring gene STARR-seq mESC enhancer starr_30621 Neighboring gene STARR-positive B cell enhancer ABC_E8449 Neighboring gene predicted gene, 38962 Neighboring gene elongin BC and polycomb repressive complex 2 associated protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. p140Cap Regulates the Composition and Localization of the NMDAR Complex in Synaptic Lipid Rafts. Angelini C, et al. J Neurosci, 2022 Sep 21. PMID 35953295, Free PMC Article
  2. Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons. Tafoya LC, et al. J Neurosci, 2006 Jul 26. PMID 16870728, Free PMC Article
  3. SNX17 Mediates Dendritic Spine Maturation via p140Cap. Cui Q, et al. Mol Neurobiol, 2024 Mar. PMID 37704928
  4. SNAP-25 regulates spine formation through postsynaptic binding to p140Cap. Tomasoni R, et al. Nat Commun, 2013. PMID 23868368
  5. p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization. Repetto D, et al. J Neurosci, 2014 Jan 22. PMID 24453341, Free PMC Article

See all (53) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Circ-USP9X accelerates deep vein thrombosis after fracture by acting as a miR-148b-3p sponge and upregulates SRC kinase signaling inhibitor 1.
    Title: Circ-USP9X accelerates deep vein thrombosis after fracture by acting as a miR-148b-3p sponge and upregulates SRC kinase signaling inhibitor 1.
  2. SNX17 Mediates Dendritic Spine Maturation via p140Cap.
    Title: SNX17 Mediates Dendritic Spine Maturation via p140Cap.
  3. Deletion of p140Cap in forebrain interneurons resulted in increased inhibitory synaptogenesis.
    Title: p140Cap Regulates GABAergic Synaptogenesis and Development of Hippocampal Inhibitory Circuits.
  4. Study demonstrates a critical role of presynaptic cadherin/catenin/p140Cap cell adhesion complexes in stabilizing functional synapses and spines in the developing neocortex.
    Title: A Critical Role of Presynaptic Cadherin/Catenin/p140Cap Complexes in Stabilizing Spines and Functional Synapses in the Neocortex.
  5. these results reveal a novel function of postsynaptic endophilin A1 in spine morphogenesis, stabilization and synaptic function through the regulation of p140Cap
    Title: Endophilin A1 regulates dendritic spine morphogenesis and stability through interaction with p140Cap.
  6. we here demonstrate that p140Cap is a key element for both learning and synaptic plasticity
    Title: p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization.
  7. SNAP-25 regulates the organization of the molecular apparatus needed for dendritic spine formation by recruiting and stabilizing p140Cap.
    Title: SNAP-25 regulates spine formation through postsynaptic binding to p140Cap.
  8. p140Cap immobilizes E-cadherin at the cell membrane and inhibits EGFR and Erk1/2 signalling, blocking scatter and proliferation of cancer cells.
    Title: p140Cap dual regulation of E-cadherin/EGFR cross-talk and Ras signalling in tumour cell scatter and proliferation.
  9. Our results thus provide evidence that SNAP-25 is critical for evoked GABA release during development and is expressed in the presynaptic terminals of mature GABAergic neurons.
    Title: Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (4)  1 citation

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein domain specific binding ISO
Inferred from Sequence Orthology
more info
  
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
  
enables protein kinase binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in exocytosis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of cell adhesion IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of protein secretion ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of protein tyrosine kinase activity ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of protein tyrosine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of protein tyrosine kinase activity ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of protein tyrosine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in postsynaptic actin cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of cell migration ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of cell migration ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of dendritic spine morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of dendritic spine morphogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of dendritic spine morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of synapse assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of synapse assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in substrate adhesion-dependent cell spreading ISO
Inferred from Sequence Orthology
more info
  
involved_in substrate adhesion-dependent cell spreading ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in axon ISO
Inferred from Sequence Orthology
more info
  
located_in axon ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in dendrite ISO
Inferred from Sequence Orthology
more info
  
located_in dendrite ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in filopodium ISO
Inferred from Sequence Orthology
more info
  
NOT located_in focal adhesion ISO
Inferred from Sequence Orthology
more info
 PubMed 
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
 PubMed 
is_active_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
  
located_in lamellipodium ISO
Inferred from Sequence Orthology
more info
  
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
  
is_active_in postsynaptic density IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in postsynaptic density IDA
Inferred from Direct Assay
more info
 PubMed 
located_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
  
located_in postsynaptic density ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in presynapse IDA
Inferred from Direct Assay
more info
 PubMed 
located_in synapse ISO
Inferred from Sequence Orthology
more info
  
located_in synapse ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
SRC kinase signaling inhibitor 1
Names
Snap-25-interacting protein
p130Cas-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018873.2 → NP_061361.2  SRC kinase signaling inhibitor 1

    See identical proteins and their annotated locations for NP_061361.2

    Status: VALIDATED

    Source sequence(s)
    AF040944, AK129422, AL596088, CJ061326
    Consensus CDS
    CCDS36294.1
    UniProtKB/TrEMBL
    A0A571BDG0, B1AQX9
    Related
    ENSMUSP00000103222.3, ENSMUST00000107596.9
    Conserved Domains (1) summary
    pfam03915
    Location:218 → 289
    AIP3; Actin interacting protein 3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    97400166..97466059 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030246171.2 → XP_030102031.1  SRC kinase signaling inhibitor 1 isoform X24

    UniProtKB/TrEMBL
    A0A571BG39
    Related
    ENSMUSP00000158676.2, ENSMUST00000238342.2
    Conserved Domains (3) summary
    TIGR02169
    Location:696 → 850
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1070 → 1421
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:185 → 264
    AIP3; Actin interacting protein 3

  2. XM_030246172.2 → XP_030102032.1  SRC kinase signaling inhibitor 1 isoform X25

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:679 → 833
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1053 → 1404
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:177 → 256
    AIP3; Actin interacting protein 3

  3. XM_036156862.1 → XP_036012755.1  SRC kinase signaling inhibitor 1 isoform X36

    UniProtKB/TrEMBL
    A0A571BDG0
    Related
    ENSMUSP00000158711.2, ENSMUST00000238314.2
    Conserved Domains (3) summary
    TIGR02169
    Location:719 → 873
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:218 → 315
    AIP3; Actin interacting protein 3
    NF033930
    Location:720 → 1031
    pneumo_PspA; pneumococcal surface protein A

  4. XM_017314677.3 → XP_017170166.1  SRC kinase signaling inhibitor 1 isoform X15

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:729 → 883
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1103 → 1454
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:218 → 297
    AIP3; Actin interacting protein 3

  5. XM_036156860.1 → XP_036012753.1  SRC kinase signaling inhibitor 1 isoform X20

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (4) summary
    TIGR02169
    Location:719 → 873
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1093 → 1444
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:218 → 297
    AIP3; Actin interacting protein 3
    NF033930
    Location:720 → 1031
    pneumo_PspA; pneumococcal surface protein A

  6. XM_030246182.2 → XP_030102042.1  SRC kinase signaling inhibitor 1 isoform X42

    UniProtKB/TrEMBL
    A0A571BDG0
    Conserved Domains (2) summary
    TIGR02169
    Location:719 → 873
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:218 → 297
    AIP3; Actin interacting protein 3

  7. XM_030246185.2 → XP_030102045.1  SRC kinase signaling inhibitor 1 isoform X46

    UniProtKB/TrEMBL
    A0A571BDG0
    Related
    ENSMUSP00000158656.2, ENSMUST00000238233.2
    Conserved Domains (2) summary
    TIGR02169
    Location:672 → 826
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:170 → 249
    AIP3; Actin interacting protein 3

  8. XM_030246186.1 → XP_030102046.1  SRC kinase signaling inhibitor 1 isoform X47

    UniProtKB/TrEMBL
    A0A571BDG6
    Conserved Domains (2) summary
    TIGR02169
    Location:705 → 859
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:203 → 282
    AIP3; Actin interacting protein 3

  9. XM_036156861.1 → XP_036012754.1  SRC kinase signaling inhibitor 1 isoform X23

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (4) summary
    TIGR02169
    Location:705 → 859
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1079 → 1430
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:203 → 282
    AIP3; Actin interacting protein 3
    NF033930
    Location:706 → 1017
    pneumo_PspA; pneumococcal surface protein A

  10. XM_017314679.3 → XP_017170168.1  SRC kinase signaling inhibitor 1 isoform X21

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:714 → 868
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1088 → 1439
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:203 → 282
    AIP3; Actin interacting protein 3

  11. XM_017314678.3 → XP_017170167.1  SRC kinase signaling inhibitor 1 isoform X21

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:714 → 868
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1088 → 1439
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:203 → 282
    AIP3; Actin interacting protein 3

  12. XM_017314674.3 → XP_017170163.1  SRC kinase signaling inhibitor 1 isoform X12

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (2) summary
    TIGR02169
    Location:784 → 938
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  13. XM_017314669.3 → XP_017170158.1  SRC kinase signaling inhibitor 1 isoform X6

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:763 → 917
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1137 → 1488
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:252 → 331
    AIP3; Actin interacting protein 3

  14. XM_017314670.3 → XP_017170159.1  SRC kinase signaling inhibitor 1 isoform X7

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:751 → 905
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1125 → 1476
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:240 → 319
    AIP3; Actin interacting protein 3

  15. XM_017314668.3 → XP_017170157.1  SRC kinase signaling inhibitor 1 isoform X3

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:776 → 930
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1150 → 1501
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:265 → 344
    AIP3; Actin interacting protein 3

  16. XM_017314667.3 → XP_017170156.1  SRC kinase signaling inhibitor 1 isoform X2

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:783 → 937
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1157 → 1508
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  17. XM_017314672.3 → XP_017170161.1  SRC kinase signaling inhibitor 1 isoform X8

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (2) summary
    TIGR02169
    Location:784 → 938
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  18. XM_017314666.3 → XP_017170155.1  SRC kinase signaling inhibitor 1 isoform X1

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:784 → 938
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1158 → 1509
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  19. XM_030246167.2 → XP_030102027.1  SRC kinase signaling inhibitor 1 isoform X17

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:722 → 876
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1096 → 1447
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:211 → 290
    AIP3; Actin interacting protein 3

  20. XM_030246169.2 → XP_030102029.1  SRC kinase signaling inhibitor 1 isoform X19

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:720 → 874
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1094 → 1445
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:219 → 298
    AIP3; Actin interacting protein 3

  21. XM_036156859.1 → XP_036012752.1  SRC kinase signaling inhibitor 1 isoform X14

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (4) summary
    TIGR02169
    Location:733 → 887
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1107 → 1458
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:232 → 311
    AIP3; Actin interacting protein 3
    NF033930
    Location:734 → 1045
    pneumo_PspA; pneumococcal surface protein A

  22. XM_017314671.3 → XP_017170160.1  SRC kinase signaling inhibitor 1 isoform X9

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:743 → 897
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1117 → 1468
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:232 → 311
    AIP3; Actin interacting protein 3

  23. XM_030246163.2 → XP_030102023.1  SRC kinase signaling inhibitor 1 isoform X11

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:741 → 895
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1115 → 1466
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:240 → 319
    AIP3; Actin interacting protein 3

  24. XM_030246162.2 → XP_030102022.1  SRC kinase signaling inhibitor 1 isoform X5

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:774 → 928
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1148 → 1499
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  25. XM_006533765.5 → XP_006533828.1  SRC kinase signaling inhibitor 1 isoform X4

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:775 → 929
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1149 → 1500
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  26. XM_030246170.2 → XP_030102030.1  SRC kinase signaling inhibitor 1 isoform X22

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:713 → 867
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1087 → 1438
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:211 → 290
    AIP3; Actin interacting protein 3

  27. XM_030246168.2 → XP_030102028.1  SRC kinase signaling inhibitor 1 isoform X18

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:721 → 875
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1095 → 1446
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:219 → 298
    AIP3; Actin interacting protein 3

  28. XM_017314680.3 → XP_017170169.1  SRC kinase signaling inhibitor 1 isoform X26

    UniProtKB/TrEMBL
    A0A571BDG0
    Conserved Domains (2) summary
    TIGR02169
    Location:784 → 938
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  29. XM_030246173.2 → XP_030102033.1  SRC kinase signaling inhibitor 1 isoform X27

    UniProtKB/TrEMBL
    A0A571BDG0
    Conserved Domains (2) summary
    TIGR02169
    Location:775 → 929
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  30. XM_030246174.2 → XP_030102034.1  SRC kinase signaling inhibitor 1 isoform X29

    UniProtKB/Swiss-Prot
    O70298, Q9QWI6
    Conserved Domains (2) summary
    TIGR02169
    Location:783 → 937
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  31. XM_030246180.2 → XP_030102040.1  SRC kinase signaling inhibitor 1 isoform X40

    UniProtKB/Swiss-Prot
    O70298, Q9QWI6
    Conserved Domains (2) summary
    TIGR02169
    Location:783 → 937
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  32. XM_017314681.3 → XP_017170170.1  SRC kinase signaling inhibitor 1 isoform X28

    UniProtKB/Swiss-Prot
    O70298, Q9QWI6
    Conserved Domains (2) summary
    TIGR02169
    Location:784 → 938
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  33. XM_030246179.2 → XP_030102039.1  SRC kinase signaling inhibitor 1 isoform X39

    UniProtKB/Swiss-Prot
    O70298, Q9QWI6
    Conserved Domains (2) summary
    TIGR02169
    Location:784 → 938
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  34. XM_030246177.2 → XP_030102037.1  SRC kinase signaling inhibitor 1 isoform X34

    UniProtKB/TrEMBL
    A0A571BDG0
    Conserved Domains (2) summary
    TIGR02169
    Location:733 → 887
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:232 → 311
    AIP3; Actin interacting protein 3

  35. XM_006533781.5 → XP_006533844.1  SRC kinase signaling inhibitor 1 isoform X38

    UniProtKB/Swiss-Prot
    O70298, Q9QWI6
    Conserved Domains (2) summary
    TIGR02169
    Location:741 → 895
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:240 → 319
    AIP3; Actin interacting protein 3

  36. XM_030246183.2 → XP_030102043.1  SRC kinase signaling inhibitor 1 isoform X43

    UniProtKB/TrEMBL
    A0A571BDG6
    Conserved Domains (2) summary
    TIGR02169
    Location:751 → 905
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:240 → 319
    AIP3; Actin interacting protein 3

  37. XM_030246175.2 → XP_030102035.1  SRC kinase signaling inhibitor 1 isoform X32

    UniProtKB/Swiss-Prot
    O70298, Q9QWI6
    Conserved Domains (2) summary
    TIGR02169
    Location:774 → 928
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  38. XM_006533779.5 → XP_006533842.1  SRC kinase signaling inhibitor 1 isoform X31

    UniProtKB/Swiss-Prot
    O70298, Q9QWI6
    Conserved Domains (2) summary
    TIGR02169
    Location:775 → 929
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  39. XM_006533782.5 → XP_006533845.1  SRC kinase signaling inhibitor 1 isoform X41

    UniProtKB/Swiss-Prot
    O70298, Q9QWI6
    Conserved Domains (2) summary
    TIGR02169
    Location:775 → 929
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  40. XM_030246184.2 → XP_030102044.1  SRC kinase signaling inhibitor 1 isoform X45

    UniProtKB/TrEMBL
    A0A571BDG6, B1AQX6
    Related
    ENSMUSP00000103219.2, ENSMUST00000107593.8
    Conserved Domains (2) summary
    TIGR02169
    Location:721 → 875
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:219 → 298
    AIP3; Actin interacting protein 3

  41. XM_017314673.2 → XP_017170162.1  SRC kinase signaling inhibitor 1 isoform X10

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:743 → 897
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1117 → 1468
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:232 → 311
    AIP3; Actin interacting protein 3

  42. XM_030246165.2 → XP_030102025.1  SRC kinase signaling inhibitor 1 isoform X16

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:726 → 880
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1100 → 1451
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:224 → 303
    AIP3; Actin interacting protein 3

  43. XM_030246164.2 → XP_030102024.1  SRC kinase signaling inhibitor 1 isoform X13

    UniProtKB/TrEMBL
    A0A571BG39
    Conserved Domains (3) summary
    TIGR02169
    Location:734 → 888
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam05109
    Location:1108 → 1459
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam03915
    Location:232 → 311
    AIP3; Actin interacting protein 3

  44. XM_006533783.5 → XP_006533846.1  SRC kinase signaling inhibitor 1 isoform X44

    UniProtKB/TrEMBL
    A0A571BDG6, B1AQX7
    Related
    ENSMUSP00000103216.2, ENSMUST00000107590.9
    Conserved Domains (2) summary
    TIGR02169
    Location:721 → 875
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:219 → 298
    AIP3; Actin interacting protein 3

  45. XM_030246178.2 → XP_030102038.1  SRC kinase signaling inhibitor 1 isoform X35

    UniProtKB/Swiss-Prot
    O70298, Q9QWI6
    Conserved Domains (2) summary
    TIGR02169
    Location:774 → 928
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  46. XM_017314682.3 → XP_017170171.1  SRC kinase signaling inhibitor 1 isoform X30

    UniProtKB/Swiss-Prot
    O70298, Q9QWI6
    Conserved Domains (2) summary
    TIGR02169
    Location:784 → 938
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  47. XM_030246176.2 → XP_030102036.1  SRC kinase signaling inhibitor 1 isoform X33

    UniProtKB/Swiss-Prot
    O70298, Q9QWI6
    Conserved Domains (2) summary
    TIGR02169
    Location:775 → 929
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

  48. XM_017314683.3 → XP_017170172.1  SRC kinase signaling inhibitor 1 isoform X37

    UniProtKB/TrEMBL
    A0A571BDG6
    Conserved Domains (2) summary
    TIGR02169
    Location:784 → 938
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam03915
    Location:273 → 352
    AIP3; Actin interacting protein 3

RNA

  1. XR_001780031.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9QWI6.2 GenPept UniProtKB/Swiss-Prot:Q9QWI6

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