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Sfn stratifin [ Mus musculus (house mouse) ]

Gene ID: 55948, updated on 3-Jun-2018
Official Symbol
Sfnprovided by MGI
Official Full Name
stratifinprovided by MGI
Primary source
MGI:MGI:1891831
See related
Ensembl:ENSMUSG00000047281 Vega:OTTMUSG00000011150
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Er; Mme1; Ywhas
Orthologs
See Sfn in Genome Data Viewer
Location:
4 D2.3; 4 66.25 cM
Exon count:
1
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (133600556..133602168, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (133156471..133158083, complement)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene GPN-loop GTPase 2 Neighboring gene predicted gene, 42324 Neighboring gene zinc finger, DHHC domain containing 18 Neighboring gene predicted gene 13213

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Associated conditions

Description Tests
repeated epilation
GeneReviews: Not available

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
phosphoprotein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein domain specific binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
establishment of skin barrier IMP
Inferred from Mutant Phenotype
more info
PubMed 
intrinsic apoptotic signaling pathway in response to DNA damage ISO
Inferred from Sequence Orthology
more info
 
keratinization IMP
Inferred from Mutant Phenotype
more info
PubMed 
keratinocyte development IGI
Inferred from Genetic Interaction
more info
PubMed 
keratinocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of keratinocyte proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of cell growth IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of epidermal cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of protein export from nucleus IDA
Inferred from Direct Assay
more info
PubMed 
regulation of cell cycle IDA
Inferred from Direct Assay
more info
PubMed 
regulation of cyclin-dependent protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
regulation of epidermal cell division IMP
Inferred from Mutant Phenotype
more info
PubMed 
release of cytochrome c from mitochondria ISO
Inferred from Sequence Orthology
more info
 
skin development IGI
Inferred from Genetic Interaction
more info
PubMed 
skin development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
14-3-3 protein sigma
Names
14-3-3 sigma protein
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, sigma polypeptide

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018754.2NP_061224.2  14-3-3 protein sigma

    See identical proteins and their annotated locations for NP_061224.2

    Status: VALIDATED

    Source sequence(s)
    AA067103, AK169358, CX224942
    Consensus CDS
    CCDS18754.1
    UniProtKB/Swiss-Prot
    O70456
    Related
    ENSMUSP00000050374.3, OTTMUSP00000011953, ENSMUST00000057311.3, OTTMUST00000026117
    Conserved Domains (1) summary
    cd10019
    Location:1242
    14-3-3_sigma; 14-3-3 sigma, an isoform of 14-3-3 protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

    Range
    133600556..133602168 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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