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ACTR10 actin related protein 10 [ Homo sapiens (human) ]

Gene ID: 55860, updated on 5-Dec-2021

Summary

Official Symbol
ACTR10provided by HGNC
Official Full Name
actin related protein 10provided by HGNC
Primary source
HGNC:HGNC:17372
See related
Ensembl:ENSG00000131966
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Arp10; Arp11; ACTR11; HARP11
Expression
Ubiquitous expression in brain (RPKM 22.5), adrenal (RPKM 21.9) and 25 other tissues See more
Orthologs
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Genomic context

See ACTR10 in Genome Data Viewer
Location:
14q23.1
Exon count:
13
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (58200149..58235636)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (58666867..58702354)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene armadillo like helical domain containing 4 Neighboring gene ubiquitin A-52 residue ribosomal protein fusion product 1 pseudogene 3 Neighboring gene RNA, 7SL, cytoplasmic 598, pseudogene Neighboring gene tRNA-Lys (anticodon CTT) 1-1 Neighboring gene proteasome 20S subunit alpha 3 Neighboring gene PSMA3 antisense RNA 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in microtubule-based movement IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in retrograde axonal transport of mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in axon cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in azurophil granule lumen TAS
Traceable Author Statement
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
part_of dynactin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular region TAS
Traceable Author Statement
more info
 
located_in ficolin-1-rich granule lumen TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
actin-related protein 10
Names
actin related protein 10 homolog
actin-related protein 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018477.3NP_060947.1  actin-related protein 10

    See identical proteins and their annotated locations for NP_060947.1

    Status: VALIDATED

    Source sequence(s)
    AF220190, AL132989, CB135721
    Consensus CDS
    CCDS32090.1
    UniProtKB/Swiss-Prot
    Q9NZ32
    Related
    ENSP00000254286.4, ENST00000254286.9
    Conserved Domains (1) summary
    cl17037
    Location:14388
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    58200149..58235636
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011536962.2XP_011535264.1  actin-related protein 10 isoform X3

    Conserved Domains (1) summary
    cl17037
    Location:14191
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
  2. XM_011536960.1XP_011535262.1  actin-related protein 10 isoform X1

    Conserved Domains (2) summary
    pfam00022
    Location:14395
    Actin; Actin
    cl17037
    Location:12389
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
  3. XM_011536961.1XP_011535263.1  actin-related protein 10 isoform X2

    Conserved Domains (2) summary
    pfam00022
    Location:14376
    Actin; Actin
    cl17037
    Location:12370
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
  4. XM_011536963.3XP_011535265.1  actin-related protein 10 isoform X4

    See identical proteins and their annotated locations for XP_011535265.1

    UniProtKB/TrEMBL
    Q86SY7
    Conserved Domains (1) summary
    cl17037
    Location:8184
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
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