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TEX2 testis expressed 2 [ Homo sapiens (human) ]

Gene ID: 55852, updated on 21-Dec-2019

Summary

Official Symbol
TEX2provided by HGNC
Official Full Name
testis expressed 2provided by HGNC
Primary source
HGNC:HGNC:30884
See related
Ensembl:ENSG00000136478
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HT008; TMEM96
Expression
Broad expression in testis (RPKM 15.4), thyroid (RPKM 12.0) and 25 other tissues See more
Orthologs

Genomic context

See TEX2 in Genome Data Viewer
Location:
17q23.3
Exon count:
15
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (64147227..64263265, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (62224795..62340653, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA, C/D box 104 Neighboring gene small nucleolar RNA, H/ACA box 50C Neighboring gene small nucleolar RNA host gene 25 Neighboring gene ribosomal protein L31 pseudogene 57 Neighboring gene platelet and endothelial cell adhesion molecule 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1738, DKFZp781G0721

Gene Ontology Provided by GOA

Function Evidence Code Pubs
lipid binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
lipid transport IEA
Inferred from Electronic Annotation
more info
 
signal transduction NAS
Non-traceable Author Statement
more info
PubMed 
sphingolipid metabolic process NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
testis-expressed protein 2
Names
testis expressed sequence 2
testis-expressed sequence 2 protein
transmembrane protein 96

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001288732.2NP_001275661.1  testis-expressed protein 2 isoform 2

    See identical proteins and their annotated locations for NP_001275661.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame acceptor splice site at an internal coding exon compared to variant 1. The resulting shorter isoform (2) lacks a 7 aa protein segment compared to isoform 1. Variants 2 and 3 encode the same isoform.
    Source sequence(s)
    AA825291, AC025362, AL834251, BC036672, BC040521
    Consensus CDS
    CCDS74131.1
    UniProtKB/Swiss-Prot
    Q8IWB9
    Related
    ENSP00000463001.1, ENST00000584379.5
    Conserved Domains (1) summary
    pfam10296
    Location:825914
    DUF2404; Putative integral membrane protein conserved region (DUF2404)
  2. NM_001288733.2NP_001275662.1  testis-expressed protein 2 isoform 2

    See identical proteins and their annotated locations for NP_001275662.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains an alternate 5' non-coding exon and uses an alternate in-frame acceptor splice site at an internal coding exon compared to variant 1. The resulting shorter isoform (2) lacks a 7 aa protein segment compared to isoform 1. Variants 2 and 3 encode the same isoform.
    Source sequence(s)
    AA825291, AC025362, BC036672, BC040521, CR627433
    Consensus CDS
    CCDS74131.1
    UniProtKB/Swiss-Prot
    Q8IWB9
    Related
    ENSP00000462665.1, ENST00000583097.5
    Conserved Domains (1) summary
    pfam10296
    Location:825914
    DUF2404; Putative integral membrane protein conserved region (DUF2404)
  3. NM_018469.5NP_060939.3  testis-expressed protein 2 isoform 1

    See identical proteins and their annotated locations for NP_060939.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
    Source sequence(s)
    AA825291, AC025362, BC036672, BC040521
    Consensus CDS
    CCDS11658.1
    UniProtKB/Swiss-Prot
    Q8IWB9
    Related
    ENSP00000258991.3, ENST00000258991.7
    Conserved Domains (1) summary
    pfam10296
    Location:832921
    DUF2404; Putative integral membrane protein conserved region (DUF2404)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    64147227..64263265 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011525000.2XP_011523302.1  testis-expressed protein 2 isoform X2

    Conserved Domains (1) summary
    pfam10296
    Location:832921
    DUF2404; Putative integral membrane protein conserved region (DUF2404)
  2. XM_017024846.2XP_016880335.1  testis-expressed protein 2 isoform X3

  3. XM_011524999.1XP_011523301.1  testis-expressed protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011523301.1

    UniProtKB/Swiss-Prot
    Q8IWB9
    Conserved Domains (1) summary
    pfam10296
    Location:832921
    DUF2404; Putative integral membrane protein conserved region (DUF2404)
  4. XM_011524998.1XP_011523300.1  testis-expressed protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011523300.1

    UniProtKB/Swiss-Prot
    Q8IWB9
    Related
    ENSP00000479308.1, ENST00000615733.4
    Conserved Domains (1) summary
    pfam10296
    Location:832921
    DUF2404; Putative integral membrane protein conserved region (DUF2404)
  5. XM_017024847.2XP_016880336.1  testis-expressed protein 2 isoform X4

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