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rce1a Ras converting CAAX endopeptidase 1a [ Danio rerio (zebrafish) ]

Gene ID: 557720, updated on 14-Sep-2024

Summary

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Official Symbol
rce1aprovided by ZNC
Official Full Name
Ras converting CAAX endopeptidase 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041008-116
See related
Ensembl:ENSDARG00000077909 AllianceGenome:ZFIN:ZDB-GENE-041008-116
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7137703
Summary
Predicted to enable metalloendopeptidase activity. Predicted to be involved in CAAX-box protein processing. Predicted to act upstream of or within proteolysis. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be integral component of endoplasmic reticulum membrane. Orthologous to human RCE1 (Ras converting CAAX endopeptidase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See rce1a in Genome Data Viewer
Location:
chromosome: 7
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (18176274..18189215)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (17923917..17935898)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene pellino E3 ubiquitin protein ligase family member 3 Neighboring gene uncharacterized LOC137496162 Neighboring gene CD248 molecule, endosialin a Neighboring gene somatostatin receptor 1b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Cd248a and Cd248b in zebrafish participate in innate immune responses. Li X, et al. Front Immunol, 2022. PMID 36119065, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metalloendopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in CAAX-box protein processing IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within CAAX-box protein processing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
CAAX prenyl protease 2
Names
RCE1 homolog, prenyl protein peptidase a
XP_001919229.3
XP_021327544.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    18176274..18189215
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001919194.8 → XP_001919229.3  CAAX prenyl protease 2

    UniProtKB/TrEMBL
    A0A8M1QH78, E7FA75
    Related
    ENSDARP00000098829.2, ENSDART00000109171.5
    Conserved Domains (2) summary
    COG1266
    Location:70 → 264
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
    pfam02517
    Location:159 → 262
    Abi; CAAX protease self-immunity

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394682.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    64255..77340
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021471869.2 → XP_021327544.1  CAAX prenyl protease 2

    UniProtKB/TrEMBL
    A0A8M9PRP4
    Conserved Domains (1) summary
    pfam02517
    Location:159 → 262
    Abi; CAAX protease self-immunity
Nucleotide Protein Strain
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