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grid1b glutamate receptor, ionotropic, delta 1b [ Danio rerio (zebrafish) ]

Gene ID: 557511, updated on 12-Sep-2024

Summary

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Official Symbol
grid1bprovided by ZNC
Official Full Name
glutamate receptor, ionotropic, delta 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-121214-84
See related
Ensembl:ENSDARG00000044161 AllianceGenome:ZFIN:ZDB-GENE-121214-84
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-192n18.1
Summary
Predicted to enable glutamate receptor activity and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to act upstream of or within ion transport. Predicted to be located in membrane and synapse. Predicted to be integral component of membrane. Predicted to be active in postsynaptic membrane. Orthologous to human GRID1 (glutamate ionotropic receptor delta type subunit 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 12
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (12112372..12835479)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (12074057..12795131)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496796 Neighboring gene uncharacterized LOC137496795 Neighboring gene uncharacterized LOC137496797 Neighboring gene uncharacterized LOC137496767 Neighboring gene uncharacterized LOC137496798 Neighboring gene coiled-coil serine-rich protein 2b Neighboring gene PAT1 homolog 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables glutamate receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ligand-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
enables monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
enables signaling receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in modulation of chemical synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in synaptic transmission, glutamatergic IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in postsynaptic density membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
  
located_in synapse IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glutamate receptor ionotropic, delta-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    12112372..12835479
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009306536.4 → XP_009304811.1  glutamate receptor ionotropic, delta-1 isoform X1

    UniProtKB/TrEMBL
    A0A8M3AY56, R4GDN8
    Related
    ENSDARP00000126591.1, ENSDART00000152431.3
    Conserved Domains (4) summary
    cd06392
    Location:25 → 424
    PBP1_iGluR_delta_1; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the delta1 receptor of an orphan glutamate receptor family
    pfam00060
    Location:565 → 840
    Lig_chan; Ligand-gated ion channel
    pfam01094
    Location:36 → 400
    ANF_receptor; Receptor family ligand binding region
    cl21456
    Location:437 → 809
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

  2. XM_680591.9 → XP_685683.4  glutamate receptor ionotropic, delta-1 isoform X2

    UniProtKB/TrEMBL
    A0A8N7TDB2
    Conserved Domains (4) summary
    cd06392
    Location:25 → 424
    PBP1_iGluR_delta_1; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the delta1 receptor of an orphan glutamate receptor family
    pfam00060
    Location:565 → 840
    Lig_chan; Ligand-gated ion channel
    pfam01094
    Location:36 → 400
    ANF_receptor; Receptor family ligand binding region
    cl21456
    Location:437 → 809
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

  3. XM_021480270.2 → XP_021335945.1  glutamate receptor ionotropic, delta-1 isoform X3

    UniProtKB/TrEMBL
    A0A8M9QMU9
    Conserved Domains (2) summary
    cd06392
    Location:25 → 424
    PBP1_iGluR_delta_1; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the delta1 receptor of an orphan glutamate receptor family
    cl21456
    Location:437 → 809
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily
Nucleotide Protein
Heading Accession and Version

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