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CNOT11 CCR4-NOT transcription complex subunit 11 [ Homo sapiens (human) ]

Gene ID: 55571, updated on 9-Feb-2020

Summary

Official Symbol
CNOT11provided by HGNC
Official Full Name
CCR4-NOT transcription complex subunit 11provided by HGNC
Primary source
HGNC:HGNC:25217
See related
Ensembl:ENSG00000158435
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C40; C2orf29
Expression
Ubiquitous expression in testis (RPKM 19.6), placenta (RPKM 16.9) and 25 other tissues See more
Orthologs

Genomic context

See CNOT11 in Genome Data Viewer
Location:
2q11.2
Exon count:
7
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (101252886..101270316)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (101869345..101886778)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene TBC1 domain family member 8 Neighboring gene VISTA enhancer hs1933 Neighboring gene TBC1D8 antisense RNA 1 Neighboring gene uncharacterized LOC105373511 Neighboring gene small nucleolar RNA, C/D box 89 Neighboring gene ring finger protein 149 Neighboring gene uncharacterized LOC105373512 Neighboring gene microRNA 5696

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS
Traceable Author Statement
more info
 
cell proliferation NAS
Non-traceable Author Statement
more info
PubMed 
gene silencing by RNA IEA
Inferred from Electronic Annotation
more info
 
nuclear-transcribed mRNA poly(A) tail shortening TAS
Traceable Author Statement
more info
 
regulation of translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
CCR4-NOT complex IDA
Inferred from Direct Assay
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
CCR4-NOT transcription complex subunit 11
Names
UPF0760 protein C2orf29

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017546.5NP_060016.3  CCR4-NOT transcription complex subunit 11

    See identical proteins and their annotated locations for NP_060016.3

    Status: VALIDATED

    Source sequence(s)
    BC018664, BM923954, BX394182
    Consensus CDS
    CCDS2050.1
    UniProtKB/Swiss-Prot
    Q9UKZ1
    Related
    ENSP00000289382.3, ENST00000289382.8
    Conserved Domains (1) summary
    pfam10155
    Location:371495
    DUF2363; Uncharacterized conserved protein (DUF2363)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    101252886..101270316
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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