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Cnot11 CCR4-NOT transcription complex, subunit 11 [ Mus musculus (house mouse) ]

Gene ID: 52846, updated on 9-May-2024

Summary

Official Symbol
Cnot11provided by MGI
Official Full Name
CCR4-NOT transcription complex, subunit 11provided by MGI
Primary source
MGI:MGI:106580
See related
Ensembl:ENSMUSG00000003135 AllianceGenome:MGI:106580
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C40; D1Bwg0212e; 2410015L18Rik
Summary
Predicted to be involved in mRNA catabolic process and negative regulation of translation. Predicted to act upstream of or within gene silencing by RNA and regulation of translation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of CCR4-NOT complex. Orthologous to human CNOT11 (CCR4-NOT transcription complex subunit 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 16.9), ovary adult (RPKM 16.4) and 28 other tissues See more
Orthologs
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Genomic context

See Cnot11 in Genome Data Viewer
Location:
1 B; 1 18.31 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (39574782..39585962)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (39535701..39546881)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L31 Neighboring gene TBC1 domain family, member 8 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:39535681-39535790 Neighboring gene STARR-seq mESC enhancer starr_00719 Neighboring gene STARR-seq mESC enhancer starr_00720 Neighboring gene STARR-seq mESC enhancer starr_00721 Neighboring gene STARR-positive B cell enhancer ABC_E7719 Neighboring gene predicted gene, 24826 Neighboring gene STARR-positive B cell enhancer ABC_E3270 Neighboring gene predicted gene, 53550 Neighboring gene small nucleolar RNA, C/D box 89 Neighboring gene predicted gene, 18446

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of translation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulatory ncRNA-mediated gene silencing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of CCR4-NOT complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of CCR4-NOT complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
CCR4-NOT transcription complex subunit 11
Names
UPF0760 protein C2orf29 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028043.3NP_082319.1  CCR4-NOT transcription complex subunit 11

    See identical proteins and their annotated locations for NP_082319.1

    Status: VALIDATED

    Source sequence(s)
    BC049091, DV649843
    Consensus CDS
    CCDS14906.1
    UniProtKB/Swiss-Prot
    Q3TJG9, Q9CWN7
    Related
    ENSMUSP00000003219.9, ENSMUST00000003219.14
    Conserved Domains (1) summary
    pfam10155
    Location:366490
    DUF2363; Uncharacterized conserved protein (DUF2363)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    39574782..39585962
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)