tbcc tubulin folding cofactor C [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tbccprovided by ZNC
Official Full Name: tubulin folding cofactor Cprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041008-103
See related: Ensembl:ENSDARG00000022918 AllianceGenome:ZFIN:ZDB-GENE-041008-103
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: tbccl; im:7137439
Summary: Predicted to enable tubulin binding activity. Predicted to be involved in protein folding and tubulin complex assembly. Predicted to act upstream of or within cell morphogenesis and post-chaperonin tubulin folding pathway. Predicted to be active in cytoplasm. Orthologous to human TBCC (tubulin folding cofactor C). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (34891576..34892827)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (34790513..34791764)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables tubulin binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within post-chaperonin tubulin folding pathway	IEA Inferred from Electronic Annotation more info
involved_in protein folding	IBA Inferred from Biological aspect of Ancestor more info
involved_in tubulin complex assembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: tubulin-specific chaperone C

Names: tubulin-specific chaperone c-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001256248.1 → NP_001243177.1 tubulin-specific chaperone C

Status: VALIDATED

Source sequence(s)

EH518082, EH552995

UniProtKB/TrEMBL

A0A8M1P2I5, F1QJC8

Related

ENSDARP00000015151.7, ENSDART00000015643.8

Conserved Domains (2) summary

pfam07986
Location:199 → 316

TBCC; Tubulin binding cofactor C

pfam16752
Location:29 → 137

TBCC_N; Tubulin-specific chaperone C N-terminal domain