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SLC39A9 solute carrier family 39 member 9 [ Homo sapiens (human) ]

Gene ID: 55334, updated on 1-Jun-2020

Summary

Official Symbol
SLC39A9provided by HGNC
Official Full Name
solute carrier family 39 member 9provided by HGNC
Primary source
HGNC:HGNC:20182
See related
Ensembl:ENSG00000029364
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZIP9; ZIP-9
Expression
Ubiquitous expression in thyroid (RPKM 15.0), kidney (RPKM 14.8) and 25 other tissues See more
Orthologs

Genomic context

See SLC39A9 in Genome Data Viewer
Location:
14q24.1
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (69398374..69462390)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (69865096..69929107)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene polypeptide N-acetylgalactosaminyltransferase 16 Neighboring gene uncharacterized LOC105370549 Neighboring gene ERH mRNA splicing and mitosis factor Neighboring gene pleckstrin homology and coiled-coil domain containing D1 Neighboring gene RPL24 pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11274, MGC74989

Gene Ontology Provided by GOA

Function Evidence Code Pubs
metal ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
zinc ion transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc transporter ZIP9
Names
solute carrier family 39 (zinc transporter), member 9
zinc transporter SLC39A9
zrt- and Irt-like protein 9

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252148.2NP_001239077.1  zinc transporter ZIP9 isoform 2

    See identical proteins and their annotated locations for NP_001239077.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AL137760, AY358687, AY780789, BX643103, DA112731
    Consensus CDS
    CCDS58328.1
    UniProtKB/Swiss-Prot
    Q9NUM3
    Related
    ENSP00000451833.1, ENST00000557046.1
    Conserved Domains (1) summary
    cl00437
    Location:9278
    Zip; ZIP Zinc transporter
  2. NM_001252150.2NP_001239079.1  zinc transporter ZIP9 isoform 3

    See identical proteins and their annotated locations for NP_001239079.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AA884056, AK222547, BC047682, BP269907
    Consensus CDS
    CCDS58327.1
    UniProtKB/Swiss-Prot
    Q9NUM3
    Related
    ENSP00000452385.1, ENST00000556605.5
    Conserved Domains (1) summary
    cl00437
    Location:9220
    Zip; ZIP Zinc transporter
  3. NM_001252151.2NP_001239080.1  zinc transporter ZIP9 isoform 4

    See identical proteins and their annotated locations for NP_001239080.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and uses a downstream, in-frame start codon, compared to variant 1. Variants 4 and 5 both encode isoform (4), which has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AK293222, AL137760, AY358687, BP299863
    UniProtKB/Swiss-Prot
    Q9NUM3
    UniProtKB/TrEMBL
    B4DDK0
    Conserved Domains (1) summary
    cl00437
    Location:13183
    Zip; ZIP Zinc transporter
  4. NM_001252152.2NP_001239081.1  zinc transporter ZIP9 isoform 4

    See identical proteins and their annotated locations for NP_001239081.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, includes an alternate internal exon and uses a downstream, in-frame start codon, compared to variant 1. Variants 4 and 5 both encode isoform (4), which has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AK316381, AL137760, AY358687, BP299863
    UniProtKB/Swiss-Prot
    Q9NUM3
    UniProtKB/TrEMBL
    B4DDK0
    Conserved Domains (1) summary
    cl00437
    Location:13183
    Zip; ZIP Zinc transporter
  5. NM_001330185.2NP_001317114.1  zinc transporter ZIP9 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks an exon in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (5) is shorter than isoform 1.
    Source sequence(s)
    AL137760, AL157996
    Consensus CDS
    CCDS81816.1
    UniProtKB/TrEMBL
    M0QX28
    Related
    ENSP00000468864.1, ENST00000031146.8
    Conserved Domains (1) summary
    cl00437
    Location:68235
    Zip; ZIP Zinc transporter
  6. NM_018375.5NP_060845.2  zinc transporter ZIP9 isoform 1

    See identical proteins and their annotated locations for NP_060845.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AL137760, AY358687, DA112731
    Consensus CDS
    CCDS9795.1
    UniProtKB/Swiss-Prot
    Q9NUM3
    UniProtKB/TrEMBL
    C4N9M8
    Related
    ENSP00000336887.5, ENST00000336643.10
    Conserved Domains (1) summary
    pfam02535
    Location:9301
    Zip; ZIP Zinc transporter

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    69398374..69462390
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024449648.1XP_024305416.1  zinc transporter ZIP9 isoform X1

    Conserved Domains (1) summary
    cl00437
    Location:13183
    Zip; ZIP Zinc transporter
  2. XM_017021426.2XP_016876915.1  zinc transporter ZIP9 isoform X1

    UniProtKB/TrEMBL
    B4DDK0
    Conserved Domains (1) summary
    cl00437
    Location:13183
    Zip; ZIP Zinc transporter
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