Format

Send to:

Choose Destination

CEP55 centrosomal protein 55 [ Homo sapiens (human) ]

Gene ID: 55165, updated on 1-Aug-2020

Summary

Official Symbol
CEP55provided by HGNC
Official Full Name
centrosomal protein 55provided by HGNC
Primary source
HGNC:HGNC:1161
See related
Ensembl:ENSG00000138180 MIM:610000
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT111; MARCH; URCC6; C10orf3
Expression
Broad expression in testis (RPKM 13.8), lymph node (RPKM 8.3) and 14 other tissues See more
Orthologs

Genomic context

See CEP55 in Genome Data Viewer
Location:
10q23.33
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (93496612..93529094)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (95256369..95288849)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene ribosomal protein L17 pseudogene 34 Neighboring gene myoferlin Neighboring gene RNA, 5S ribosomal pseudogene 323 Neighboring gene uncharacterized LOC105378436 Neighboring gene free fatty acid receptor 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10540

Gene Ontology Provided by GOA

Function Evidence Code Pubs
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cranial skeletal system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
establishment of protein localization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
establishment of protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
midbody abscission IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic cytokinesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitotic cytokinesis IGI
Inferred from Genetic Interaction
more info
PubMed 
NOT mitotic metaphase plate congression IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
NOT nucleus organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of phosphatidylinositol 3-kinase signaling IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Flemming body IDA
Inferred from Direct Assay
more info
PubMed 
centriolar satellite IDA
Inferred from Direct Assay
more info
 
centriole IEA
Inferred from Electronic Annotation
more info
 
centrosome IDA
Inferred from Direct Assay
more info
PubMed 
cleavage furrow IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
intercellular bridge IEA
Inferred from Electronic Annotation
more info
 
membrane HDA PubMed 
midbody IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
midbody IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
centrosomal protein of 55 kDa
Names
cancer/testis antigen 111
centrosomal protein 55kDa
up-regulated in colon cancer 6

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127182.2NP_001120654.2  centrosomal protein of 55 kDa

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) results from use of an alternate splice donor site for exon 1.
    Source sequence(s)
    AL356214
    Consensus CDS
    CCDS7428.1
    Conserved Domains (1) summary
    COG1196
    Location:21405
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  2. NM_018131.5NP_060601.4  centrosomal protein of 55 kDa

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) results from use of an alternate splice donor site for exon 1.
    Source sequence(s)
    AL356214
    Consensus CDS
    CCDS7428.1
    Related
    ENSP00000360540.3, ENST00000371485.8
    Conserved Domains (1) summary
    COG1196
    Location:21405
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    93496612..93529094
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011539919.1XP_011538221.1  centrosomal protein of 55 kDa isoform X1

    See identical proteins and their annotated locations for XP_011538221.1

    Conserved Domains (1) summary
    pfam12180
    Location:235
    EABR; TSG101 and ALIX binding domain of CEP55
  2. XM_011539918.1XP_011538220.1  centrosomal protein of 55 kDa isoform X1

    See identical proteins and their annotated locations for XP_011538220.1

    Conserved Domains (1) summary
    pfam12180
    Location:235
    EABR; TSG101 and ALIX binding domain of CEP55
  3. XM_017016373.1XP_016871862.1  centrosomal protein of 55 kDa isoform X1

    Conserved Domains (1) summary
    pfam12180
    Location:235
    EABR; TSG101 and ALIX binding domain of CEP55
  4. XM_017016372.1XP_016871861.1  centrosomal protein of 55 kDa isoform X1

    Conserved Domains (1) summary
    pfam12180
    Location:235
    EABR; TSG101 and ALIX binding domain of CEP55
  5. XM_011539920.2XP_011538222.1  centrosomal protein of 55 kDa isoform X1

    See identical proteins and their annotated locations for XP_011538222.1

    Conserved Domains (1) summary
    pfam12180
    Location:235
    EABR; TSG101 and ALIX binding domain of CEP55
Support Center