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alkbh8 alkB homolog 8, tRNA methyltransferase [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 550051, updated on 18-Sep-2024

Summary

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Official Symbol
alkbh8provided by Xenbase
Official Full Name
alkB homolog 8, tRNA methyltransferaseprovided by Xenbase
Primary source
Xenbase:XB-GENE-985927
See related
Ensembl:ENSXETG00000014487
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
13
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (160135591..160155326)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (157051170..157072439)

Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene sarcolipin Neighboring gene ELMO/CED-12 domain containing 1 Neighboring gene uncharacterized LOC100492546 Neighboring gene CWF19 like cell cycle control factor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables S-adenosylmethionine-dependent methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tRNA methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within RNA metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within gene expression IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within macromolecule modification IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tRNA wobble uridine modification IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
alkylated DNA repair protein alkB homolog 8
Names
S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8
alkB, alkylation repair homolog 8
probable alpha-ketoglutarate-dependent dioxygenase ABH8
tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8
NP_001017297.2
XP_012812512.2
XP_012812513.2
XP_012812514.2
XP_012812515.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017297.3 → NP_001017297.2  alkylated DNA repair protein alkB homolog 8

    Status: VALIDATED

    Source sequence(s)
    CR855607, CX511363
    UniProtKB/Swiss-Prot
    Q07G10
    Related
    ENSXETP00000031718.5, ENSXETT00000031718.5
    Conserved Domains (4) summary
    COG0724
    Location:39 → 108
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12431
    Location:42 → 120
    RRM_ALKBH8; RNA recognition motif in alkylated DNA repair protein alkB homolog 8 (ALKBH8) and similar proteins
    pfam08241
    Location:411 → 500
    Methyltransf_11; Methyltransferase domain
    cl21496
    Location:137 → 332
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    160135591..160155326
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012957059.3 → XP_012812513.2  alkylated DNA repair protein alkB homolog 8 isoform X2

    UniProtKB/Swiss-Prot
    Q07G10
    UniProtKB/TrEMBL
    A0A8J0SCU5
    Conserved Domains (3) summary
    pfam13649
    Location:416 → 503
    Methyltransf_25; Methyltransferase domain
    cd12431
    Location:49 → 127
    RRM_ALKBH8; RNA recognition motif (RRM) found in alkylated DNA repair protein alkB homolog 8 (ALKBH8) and similar proteins
    cl21496
    Location:144 → 339
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily

  2. XM_012957058.3 → XP_012812512.2  alkylated DNA repair protein alkB homolog 8 isoform X1

    UniProtKB/Swiss-Prot
    Q07G10
    UniProtKB/TrEMBL
    A0A8J0SFV0
    Conserved Domains (3) summary
    pfam13649
    Location:419 → 506
    Methyltransf_25; Methyltransferase domain
    cd12431
    Location:52 → 130
    RRM_ALKBH8; RNA recognition motif (RRM) found in alkylated DNA repair protein alkB homolog 8 (ALKBH8) and similar proteins
    cl21496
    Location:147 → 342
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily

  3. XM_012957061.3 → XP_012812515.2  alkylated DNA repair protein alkB homolog 8 isoform X3

    UniProtKB/Swiss-Prot
    Q07G10
    UniProtKB/TrEMBL
    A0A8J0SFR5
    Conserved Domains (3) summary
    pfam13649
    Location:409 → 496
    Methyltransf_25; Methyltransferase domain
    cd12431
    Location:42 → 120
    RRM_ALKBH8; RNA recognition motif (RRM) found in alkylated DNA repair protein alkB homolog 8 (ALKBH8) and similar proteins
    cl21496
    Location:137 → 332
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily

  4. XM_012957060.3 → XP_012812514.2  alkylated DNA repair protein alkB homolog 8 isoform X3

    UniProtKB/Swiss-Prot
    Q07G10
    UniProtKB/TrEMBL
    A0A8J0SFR5
    Conserved Domains (3) summary
    pfam13649
    Location:409 → 496
    Methyltransf_25; Methyltransferase domain
    cd12431
    Location:42 → 120
    RRM_ALKBH8; RNA recognition motif (RRM) found in alkylated DNA repair protein alkB homolog 8 (ALKBH8) and similar proteins
    cl21496
    Location:137 → 332
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q07G10.2 GenPept UniProtKB/Swiss-Prot:Q07G10

Gene LinkOut

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