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QRICH1 glutamine rich 1 [ Homo sapiens (human) ]

Gene ID: 54870, updated on 20-Dec-2019

Summary

Official Symbol
QRICH1provided by HGNC
Official Full Name
glutamine rich 1provided by HGNC
Primary source
HGNC:HGNC:24713
See related
Ensembl:ENSG00000198218 MIM:617387
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AB-DIP; VERBRAS
Expression
Ubiquitous expression in testis (RPKM 28.0), bone marrow (RPKM 21.2) and 25 other tissues See more
Orthologs

Genomic context

See QRICH1 in Genome Data Viewer
Location:
3p21.31
Exon count:
13
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (49029707..49094373, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (49067140..49131504, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene DALR anticodon binding domain containing 3 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 3 Neighboring gene microRNA 425 Neighboring gene microRNA 191 Neighboring gene inosine monophosphate dehydrogenase 2 Neighboring gene RNA, 7SL, cytoplasmic 182, pseudogene Neighboring gene glutaminyl-tRNA synthetase 1 Neighboring gene microRNA 6890 Neighboring gene ubiquitin specific peptidase 19

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20259, MGC131838

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
regulation of cell morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001320580.1NP_001307509.1  glutamine-rich protein 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-8 encode the same protein.
    Source sequence(s)
    AK292536, BC000978, BC110855, DA238657
    Consensus CDS
    CCDS2787.1
    UniProtKB/Swiss-Prot
    Q2TAL8
    UniProtKB/TrEMBL
    A1L3Z9
    Related
    ENSP00000412890.1, ENST00000424300.5
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:599758
    DUF3504; Domain of unknown function (DUF3504)
  2. NM_001320581.1NP_001307510.1  glutamine-rich protein 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-8 encode the same protein.
    Source sequence(s)
    BC000978, BC110855, DA238657, DB062422
    Consensus CDS
    CCDS2787.1
    UniProtKB/Swiss-Prot
    Q2TAL8
    UniProtKB/TrEMBL
    A1L3Z9
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:599758
    DUF3504; Domain of unknown function (DUF3504)
  3. NM_001320582.1NP_001307511.1  glutamine-rich protein 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-8 encode the same protein.
    Source sequence(s)
    BC000978, BC110855, DA238657, DB062061
    Consensus CDS
    CCDS2787.1
    UniProtKB/Swiss-Prot
    Q2TAL8
    UniProtKB/TrEMBL
    A1L3Z9
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:599758
    DUF3504; Domain of unknown function (DUF3504)
  4. NM_001320583.1NP_001307512.1  glutamine-rich protein 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1-8 encode the same protein.
    Source sequence(s)
    BC000978, BC110855, DA238657, DB062828
    Consensus CDS
    CCDS2787.1
    UniProtKB/Swiss-Prot
    Q2TAL8
    UniProtKB/TrEMBL
    A1L3Z9
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:599758
    DUF3504; Domain of unknown function (DUF3504)
  5. NM_001320584.1NP_001307513.1  glutamine-rich protein 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1-8 encode the same protein.
    Source sequence(s)
    AC135506, BC000978, BC110855, DA388875
    Consensus CDS
    CCDS2787.1
    UniProtKB/Swiss-Prot
    Q2TAL8
    UniProtKB/TrEMBL
    A1L3Z9
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:599758
    DUF3504; Domain of unknown function (DUF3504)
  6. NM_001320585.1NP_001307514.1  glutamine-rich protein 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. Variants 1-8 encode the same protein.
    Source sequence(s)
    AC135506, BC000978, BC110855, HY006215
    Consensus CDS
    CCDS2787.1
    UniProtKB/Swiss-Prot
    Q2TAL8
    UniProtKB/TrEMBL
    A1L3Z9
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:599758
    DUF3504; Domain of unknown function (DUF3504)
  7. NM_017730.3NP_060200.2  glutamine-rich protein 1

    See identical proteins and their annotated locations for NP_060200.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1-8 encode the same protein.
    Source sequence(s)
    AC135506, AK025013, AK074313, BC000978, BC110855, DA241522
    Consensus CDS
    CCDS2787.1
    UniProtKB/Swiss-Prot
    Q2TAL8
    UniProtKB/TrEMBL
    A1L3Z9
    Related
    ENSP00000350094.2, ENST00000357496.6
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:599758
    DUF3504; Domain of unknown function (DUF3504)
  8. NM_198880.3NP_942581.1  glutamine-rich protein 1

    See identical proteins and their annotated locations for NP_942581.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-8 encode the same protein.
    Source sequence(s)
    AK025013, AK074313, AW673597, BC000978, BC110855, DA241522
    Consensus CDS
    CCDS2787.1
    UniProtKB/Swiss-Prot
    Q2TAL8
    UniProtKB/TrEMBL
    A1L3Z9
    Related
    ENSP00000378830.2, ENST00000395443.7
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:599758
    DUF3504; Domain of unknown function (DUF3504)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    49029707..49094373 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011533863.1XP_011532165.1  glutamine-rich protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011532165.1

    UniProtKB/Swiss-Prot
    Q2TAL8
    UniProtKB/TrEMBL
    A1L3Z9
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:599758
    DUF3504; Domain of unknown function (DUF3504)
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