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Qrich1 glutamine-rich 1 [ Mus musculus (house mouse) ]

Gene ID: 69232, updated on 5-Mar-2024

Summary

Official Symbol
Qrich1provided by MGI
Official Full Name
glutamine-rich 1provided by MGI
Primary source
MGI:MGI:1916482
See related
Ensembl:ENSMUSG00000006673 AllianceGenome:MGI:1916482
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
b2b2404Clo; 2610028H07Rik
Summary
Predicted to enable DNA binding activity. Involved in response to endoplasmic reticulum stress. Acts upstream of or within kidney development. Predicted to be located in nucleoplasm. Is expressed in female reproductive system and urinary system. Orthologous to human QRICH1 (glutamine rich 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 54.1), ovary adult (RPKM 39.6) and 28 other tissues See more
Orthologs
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Genomic context

Location:
9 F2; 9 59.45 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (108394010..108437366)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (108516982..108560167)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E2916 Neighboring gene ubiquitin specific peptidase 19 Neighboring gene STARR-positive B cell enhancer ABC_E3860 Neighboring gene glutaminyl-tRNA synthetase 1 Neighboring gene STARR-positive B cell enhancer ABC_E3861 Neighboring gene STARR-positive B cell enhancer ABC_E3862 Neighboring gene inosine monophosphate dehydrogenase 2 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Chemically induced (ENU) (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transcriptional regulator QRICH1
Names
glutamine-rich protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001114119.1NP_001107591.1  transcriptional regulator QRICH1

    See identical proteins and their annotated locations for NP_001107591.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK151491, BB851544, BF658891, CT010508
    Consensus CDS
    CCDS52927.1
    UniProtKB/Swiss-Prot
    Q3UA37
    UniProtKB/TrEMBL
    G3X8R5
    Related
    ENSMUSP00000006851.9, ENSMUST00000006851.15
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:606759
    DUF3504; Domain of unknown function (DUF3504)
  2. NM_175143.5NP_780352.2  transcriptional regulator QRICH1

    See identical proteins and their annotated locations for NP_780352.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant lacks an exon in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK151491, BB851544, BC120916, BF658891
    Consensus CDS
    CCDS52927.1
    UniProtKB/Swiss-Prot
    Q3UA37
    UniProtKB/TrEMBL
    G3X8R5
    Related
    ENSMUSP00000107782.4, ENSMUST00000112155.9
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:606759
    DUF3504; Domain of unknown function (DUF3504)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    108394010..108437366
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006511809.4XP_006511872.1  transcriptional regulator QRICH1 isoform X1

    See identical proteins and their annotated locations for XP_006511872.1

    UniProtKB/Swiss-Prot
    Q3UA37
    UniProtKB/TrEMBL
    G3X8R5
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:606759
    DUF3504; Domain of unknown function (DUF3504)
  2. XM_030244560.2XP_030100420.1  transcriptional regulator QRICH1 isoform X2

    UniProtKB/Swiss-Prot
    Q3UA37
    Conserved Domains (1) summary
    pfam12012
    Location:507667
    DUF3504; Domain of unknown function (DUF3504)
  3. XM_006511808.4XP_006511871.1  transcriptional regulator QRICH1 isoform X1

    See identical proteins and their annotated locations for XP_006511871.1

    UniProtKB/Swiss-Prot
    Q3UA37
    UniProtKB/TrEMBL
    G3X8R5
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:606759
    DUF3504; Domain of unknown function (DUF3504)
  4. XM_017313561.3XP_017169050.1  transcriptional regulator QRICH1 isoform X4

    Conserved Domains (2) summary
    pfam12012
    Location:256416
    DUF3504; Domain of unknown function (DUF3504)
    cl14633
    Location:645
    DD; Death Domain Superfamily of protein-protein interaction domains
  5. XM_006511813.4XP_006511876.1  transcriptional regulator QRICH1 isoform X1

    See identical proteins and their annotated locations for XP_006511876.1

    UniProtKB/Swiss-Prot
    Q3UA37
    UniProtKB/TrEMBL
    G3X8R5
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:606759
    DUF3504; Domain of unknown function (DUF3504)
  6. XM_006511812.3XP_006511875.1  transcriptional regulator QRICH1 isoform X1

    See identical proteins and their annotated locations for XP_006511875.1

    UniProtKB/Swiss-Prot
    Q3UA37
    UniProtKB/TrEMBL
    G3X8R5
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:606759
    DUF3504; Domain of unknown function (DUF3504)
  7. XM_006511811.5XP_006511874.1  transcriptional regulator QRICH1 isoform X1

    See identical proteins and their annotated locations for XP_006511874.1

    UniProtKB/Swiss-Prot
    Q3UA37
    UniProtKB/TrEMBL
    G3X8R5
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:606759
    DUF3504; Domain of unknown function (DUF3504)
  8. XM_006511814.3XP_006511877.1  transcriptional regulator QRICH1 isoform X1

    See identical proteins and their annotated locations for XP_006511877.1

    UniProtKB/Swiss-Prot
    Q3UA37
    UniProtKB/TrEMBL
    G3X8R5
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:606759
    DUF3504; Domain of unknown function (DUF3504)
  9. XM_006511818.2XP_006511881.1  transcriptional regulator QRICH1 isoform X4

    See identical proteins and their annotated locations for XP_006511881.1

    Conserved Domains (2) summary
    pfam12012
    Location:256416
    DUF3504; Domain of unknown function (DUF3504)
    cl14633
    Location:645
    DD; Death Domain Superfamily of protein-protein interaction domains
  10. XM_036155242.1XP_036011135.1  transcriptional regulator QRICH1 isoform X2

    UniProtKB/Swiss-Prot
    Q3UA37
    Conserved Domains (1) summary
    pfam12012
    Location:507667
    DUF3504; Domain of unknown function (DUF3504)
  11. XM_006511810.4XP_006511873.1  transcriptional regulator QRICH1 isoform X1

    See identical proteins and their annotated locations for XP_006511873.1

    UniProtKB/Swiss-Prot
    Q3UA37
    UniProtKB/TrEMBL
    G3X8R5
    Conserved Domains (2) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain
    pfam12012
    Location:606759
    DUF3504; Domain of unknown function (DUF3504)
  12. XM_036155244.1XP_036011137.1  transcriptional regulator QRICH1 isoform X4

    Conserved Domains (2) summary
    pfam12012
    Location:256416
    DUF3504; Domain of unknown function (DUF3504)
    cl14633
    Location:645
    DD; Death Domain Superfamily of protein-protein interaction domains
  13. XM_017313560.3XP_017169049.1  transcriptional regulator QRICH1 isoform X2

    UniProtKB/Swiss-Prot
    Q3UA37
    Conserved Domains (1) summary
    pfam12012
    Location:507667
    DUF3504; Domain of unknown function (DUF3504)
  14. XM_030244561.2XP_030100421.1  transcriptional regulator QRICH1 isoform X4

    Conserved Domains (2) summary
    pfam12012
    Location:256416
    DUF3504; Domain of unknown function (DUF3504)
    cl14633
    Location:645
    DD; Death Domain Superfamily of protein-protein interaction domains
  15. XM_036155243.1XP_036011136.1  transcriptional regulator QRICH1 isoform X3

    UniProtKB/TrEMBL
    Q8BUN3
    Related
    ENSMUSP00000141267.2, ENSMUST00000193258.6
    Conserved Domains (1) summary
    cd01671
    Location:645
    CARD; Caspase activation and recruitment domain: a protein-protein interaction domain