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RBFOX1 RNA binding fox-1 homolog 1 [ Homo sapiens (human) ]

Gene ID: 54715, updated on 6-Jan-2019

Summary

Official Symbol
RBFOX1provided by HGNC
Official Full Name
RNA binding fox-1 homolog 1provided by HGNC
Primary source
HGNC:HGNC:18222
See related
Ensembl:ENSG00000078328 MIM:605104
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
2BP1; FOX1; A2BP1; FOX-1; HRNBP1
Summary
The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Expression
Biased expression in brain (RPKM 11.3) and heart (RPKM 2.5) See more
Orthologs

Genomic context

See RBFOX1 in Genome Data Viewer
Location:
16p13.3
Exon count:
29
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 16 NC_000016.10 (5239752..7713343)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (5289469..7763342)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984828 Neighboring gene uncharacterized LOC105371067 Neighboring gene 40S ribosomal protein S24 pseudogene Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 7 pseudogene 14 Neighboring gene long intergenic non-protein coding RNA 2164 Neighboring gene ribosomal protein S3a pseudogene 48 Neighboring gene small nuclear ribonucleoprotein polypeptide C pseudogene 20 Neighboring gene nucleophosmin 1 pseudogene 3 Neighboring gene long intergenic non-protein coding RNA 1570 Neighboring gene microRNA 8065 Neighboring gene meiotic recombination hotspot CG Neighboring gene RNA, U7 small nuclear 99 pseudogene Neighboring gene RNA, U6 small nuclear 457, pseudogene Neighboring gene uncharacterized LOC105371068 Neighboring gene RNA, U6 small nuclear 328, pseudogene Neighboring gene ribosomal protein S26 pseudogene 51 Neighboring gene uncharacterized LOC105371069 Neighboring gene uncharacterized LOC105371070

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
A genome-wide association study of sleep habits and insomnia.
NHGRI GWA Catalog
A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.
NHGRI GWA Catalog
Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.
NHGRI GWA Catalog
Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.
NHGRI GWA Catalog
Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum.
NHGRI GWA Catalog
Genome-wide association and admixture analysis of glaucoma in the Women's Health Initiative.
NHGRI GWA Catalog
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
NHGRI GWA Catalog
Genome-wide association study and meta-analysis of intraocular pressure.
NHGRI GWA Catalog
Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.
NHGRI GWA Catalog
Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1.
NHGRI GWA Catalog
Genome-wide association study of chronic periodontitis in a general German population.
NHGRI GWA Catalog
Genome-Wide Association Study of Primary Dentition Pit-and-Fissure and Smooth Surface Caries.
NHGRI GWA Catalog
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.
NHGRI GWA Catalog
Genome-wide meta-analysis for severe diabetic retinopathy.
NHGRI GWA Catalog
Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 Loci.
NHGRI GWA Catalog
Genomewide association study of movement-related adverse antipsychotic effects.
NHGRI GWA Catalog
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
NHGRI GWA Catalog
Integrated Genome-wide Association, Coexpression Network, and Expression Single Nucleotide Polymorphism Analysis Identifies Novel Pathway in Allergic Rhinitis.
NHGRI GWA Catalog
Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error.
NHGRI GWA Catalog
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
NHGRI GWA Catalog

Pathways from BioSystems

  • MECP2 and Associated Rett Syndrome, organism-specific biosystem (from WikiPathways)
    MECP2 and Associated Rett Syndrome, organism-specific biosystemMecp2 is in many mammals an important regulator of neuronal function and development. It affects all cell types, especially neurons but also astrocytes, oligodendrocytes, and glial cells. Mecp2 plays...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding NAS
Non-traceable Author Statement
more info
PubMed 
mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein C-terminus binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
RNA splicing IEA
Inferred from Electronic Annotation
more info
 
RNA transport NAS
Non-traceable Author Statement
more info
PubMed 
mRNA processing IEA
Inferred from Electronic Annotation
more info
 
nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of alternative mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
trans-Golgi network IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
RNA binding protein fox-1 homolog 1
Names
RNA binding protein, fox-1 homolog 1
ataxin 2-binding protein 1
fox-1 homolog A
fox-1-like RNA-binding protein 1
hexaribonucleotide binding protein 1 isoform alpha
hexaribonucleotide binding protein 1 isoform beta
hexaribonucleotide-binding protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_011881.2 RefSeqGene

    Range
    784380..2478587
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001142333.1NP_001135805.1  RNA binding protein fox-1 homolog 1 isoform 5

    See identical proteins and their annotated locations for NP_001135805.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and has multiple coding region differences compared to variant 1. The resulting isoform (5) has a shorter and distinct N-terminus and other internal differences compared to isoform 1.
    Source sequence(s)
    AB208826, AC005774, AF448859
    Consensus CDS
    CCDS55984.1
    UniProtKB/Swiss-Prot
    Q9NWB1
    UniProtKB/TrEMBL
    Q59HD3
    Related
    ENSP00000447753.1, ENST00000553186.5
    Conserved Domains (3) summary
    cd12407
    Location:117192
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:226315
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:4122
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  2. NM_001142334.1NP_001135806.1  RNA binding protein fox-1 homolog 1 isoform 4

    See identical proteins and their annotated locations for NP_001135806.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and lacks an in-frame section of the 3' coding region, compared to variant 1. This results in a shorter isoform (4) with an alternate N-terminus compared to isoform 1. Variants 4 and 6 both encode isoform 4.
    Source sequence(s)
    AC005774, AF107203, AK001027
    Consensus CDS
    CCDS55983.1
    UniProtKB/Swiss-Prot
    Q9NWB1
    Related
    ENSP00000447717.1, ENST00000547338.5
    Conserved Domains (3) summary
    cd12407
    Location:117192
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:253342
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:4122
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  3. NM_001308117.1NP_001295046.1  RNA binding protein fox-1 homolog 1 isoform 6

    See identical proteins and their annotated locations for NP_001295046.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the UTRs and has multiple differences in the coding region which results in the use of an alternate start codon and a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (6) has a longer N-terminus and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC005774, AC027683, AK293951
    Consensus CDS
    CCDS76818.1
    UniProtKB/TrEMBL
    B7Z1U7
    Related
    ENSP00000391269.4, ENST00000422070.8
    Conserved Domains (3) summary
    cd12407
    Location:160235
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:296385
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:33165
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  4. NM_001364800.1NP_001351729.1  RNA binding protein fox-1 homolog 1 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC005774, AC007012, AC007217, AC009135, AC022206, AC027683, KF456152
    Conserved Domains (3) summary
    cd12407
    Location:117192
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:253341
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:4122
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  5. NM_018723.3NP_061193.2  RNA binding protein fox-1 homolog 1 isoform 4

    See identical proteins and their annotated locations for NP_061193.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and lacks an in-frame section of the 3' coding region, compared to variant 1. This results in a shorter isoform (4) with an alternate N-terminus compared to isoform 1. Variants 4 and 6 both encode isoform 4.
    Source sequence(s)
    AB208826, AC005774, AF107203
    Consensus CDS
    CCDS55983.1
    UniProtKB/Swiss-Prot
    Q9NWB1
    UniProtKB/TrEMBL
    Q59HD3
    Related
    ENSP00000450031.1, ENST00000550418.5
    Conserved Domains (3) summary
    cd12407
    Location:117192
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:253342
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:4122
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  6. NM_145891.2NP_665898.1  RNA binding protein fox-1 homolog 1 isoform 1

    See identical proteins and their annotated locations for NP_665898.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1), also known as gamma, encodes isoform (1).
    Source sequence(s)
    AC005774, AC007222, AF229057
    Consensus CDS
    CCDS10531.1
    UniProtKB/Swiss-Prot
    Q9NWB1
    Related
    ENSP00000309117.5, ENST00000311745.9
    Conserved Domains (3) summary
    cd12407
    Location:137212
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:273363
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:25208
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  7. NM_145892.2NP_665899.1  RNA binding protein fox-1 homolog 1 isoform 2

    See identical proteins and their annotated locations for NP_665899.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2), also known as alpha, lacks an in-frame segment of the 3' coding region, compared to variant 1. This results in a shorter isoform (2) that lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AC005774, AC007222, AF094849
    Consensus CDS
    CCDS45405.1
    UniProtKB/Swiss-Prot
    Q9NWB1
    Related
    ENSP00000402745.2, ENST00000436368.6
    Conserved Domains (3) summary
    cd12407
    Location:137212
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:273363
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:25208
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  8. NM_145893.2NP_665900.1  RNA binding protein fox-1 homolog 1 isoform 3

    See identical proteins and their annotated locations for NP_665900.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3), also known as beta, has an alternate exon in the 3' coding region, compared to variant 1. This results in a shorter isoform (3) with an alternate C-terminus, compared to isoform 1.
    Source sequence(s)
    AC005774, AC007222, AF109106
    Consensus CDS
    CCDS10532.1
    UniProtKB/Swiss-Prot
    Q9NWB1
    Related
    ENSP00000347855.4, ENST00000355637.8
    Conserved Domains (3) summary
    cd12407
    Location:137212
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:273362
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:25208
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p12 Primary Assembly

    Range
    5239752..7713343
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017023318.2XP_016878807.1  RNA binding protein fox-1 homolog 1 isoform X1

    Related
    ENSP00000493041.1, ENST00000641259.1
  2. XM_024450303.1XP_024306071.1  RNA binding protein fox-1 homolog 1 isoform X2

    Conserved Domains (4) summary
    PHA03169
    Location:18156
    PHA03169; hypothetical protein; Provisional
    cd12407
    Location:303378
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:439528
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:176308
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  3. XM_017023319.2XP_016878808.1  RNA binding protein fox-1 homolog 1 isoform X3

  4. XM_017023326.2XP_016878815.1  RNA binding protein fox-1 homolog 1 isoform X14

    Conserved Domains (4) summary
    PHA03193
    Location:45112
    PHA03193; tegument protein VP11/12; Provisional
    COG0724
    Location:100200
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:117192
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:253339
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  5. XM_017023335.2XP_016878824.1  RNA binding protein fox-1 homolog 1 isoform X34

    Conserved Domains (3) summary
    cd12407
    Location:117192
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:253341
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:4122
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  6. XM_005255390.4XP_005255447.1  RNA binding protein fox-1 homolog 1 isoform X13

    See identical proteins and their annotated locations for XP_005255447.1

    Conserved Domains (4) summary
    PHA03193
    Location:45112
    PHA03193; tegument protein VP11/12; Provisional
    COG0724
    Location:100200
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:117192
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:253340
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  7. XM_017023341.2XP_016878830.1  RNA binding protein fox-1 homolog 1 isoform X41

  8. XM_024450307.1XP_024306075.1  RNA binding protein fox-1 homolog 1 isoform X26

    Conserved Domains (3) summary
    pfam12414
    Location:222310
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:117156
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl27169
    Location:4122
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  9. XM_024450316.1XP_024306084.1  RNA binding protein fox-1 homolog 1 isoform X42

    Conserved Domains (3) summary
    pfam12414
    Location:222310
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:117156
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl27169
    Location:4122
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  10. XM_017023328.2XP_016878817.1  RNA binding protein fox-1 homolog 1 isoform X16

    Conserved Domains (4) summary
    PHA03193
    Location:88155
    PHA03193; tegument protein VP11/12; Provisional
    COG0724
    Location:143243
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:160235
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:296382
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  11. XM_017023324.2XP_016878813.1  RNA binding protein fox-1 homolog 1 isoform X10

    Conserved Domains (4) summary
    PHA03193
    Location:88155
    PHA03193; tegument protein VP11/12; Provisional
    COG0724
    Location:143243
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:160235
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:296385
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  12. XM_017023320.2XP_016878809.1  RNA binding protein fox-1 homolog 1 isoform X4

    Related
    ENSP00000446842.1, ENST00000547372.5
    Conserved Domains (4) summary
    PHA03193
    Location:88155
    PHA03193; tegument protein VP11/12; Provisional
    COG0724
    Location:143243
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:160235
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:296383
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  13. XM_024450309.1XP_024306077.1  RNA binding protein fox-1 homolog 1 isoform X29

    Conserved Domains (3) summary
    cd12407
    Location:160235
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:269357
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:33165
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  14. XM_017023329.2XP_016878818.1  RNA binding protein fox-1 homolog 1 isoform X18

    Conserved Domains (4) summary
    PHA03193
    Location:88155
    PHA03193; tegument protein VP11/12; Provisional
    COG0724
    Location:143295
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:160235
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:269358
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  15. XM_024450310.1XP_024306078.1  RNA binding protein fox-1 homolog 1 isoform X30

    Conserved Domains (3) summary
    pfam12414
    Location:265353
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:160199
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl27169
    Location:33165
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  16. XM_024450314.1XP_024306082.1  RNA binding protein fox-1 homolog 1 isoform X38

    Conserved Domains (3) summary
    pfam12414
    Location:238327
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:160199
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl27169
    Location:33165
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  17. XM_017023322.2XP_016878811.1  RNA binding protein fox-1 homolog 1 isoform X6

    Related
    ENSP00000438768.2, ENST00000535565.6
    Conserved Domains (3) summary
    cd12407
    Location:153228
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:289377
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:26158
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  18. XM_017023321.2XP_016878810.1  RNA binding protein fox-1 homolog 1 isoform X5

    Conserved Domains (4) summary
    PHA03193
    Location:81148
    PHA03193; tegument protein VP11/12; Provisional
    COG0724
    Location:136236
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:153228
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:289376
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  19. XM_017023330.1XP_016878819.1  RNA binding protein fox-1 homolog 1 isoform X20

    Related
    ENSP00000448496.1, ENST00000552089.5
  20. XM_024450304.1XP_024306072.1  RNA binding protein fox-1 homolog 1 isoform X11

    Conserved Domains (3) summary
    cd12407
    Location:153228
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:289378
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:26158
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  21. XM_024450305.1XP_024306073.1  RNA binding protein fox-1 homolog 1 isoform X12

    Conserved Domains (3) summary
    cd12407
    Location:153228
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:262350
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:26158
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  22. XM_024450311.1XP_024306079.1  RNA binding protein fox-1 homolog 1 isoform X31

    Conserved Domains (3) summary
    cd12407
    Location:153228
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:262350
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:26158
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  23. XM_024450312.1XP_024306080.1  RNA binding protein fox-1 homolog 1 isoform X32

    Conserved Domains (3) summary
    pfam12414
    Location:258346
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:153192
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl27169
    Location:26158
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  24. XM_024450313.1XP_024306081.1  RNA binding protein fox-1 homolog 1 isoform X33

    Conserved Domains (3) summary
    pfam12414
    Location:231320
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:153192
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl27169
    Location:26158
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  25. XM_017023336.1XP_016878825.1  RNA binding protein fox-1 homolog 1 isoform X34

    Conserved Domains (3) summary
    cd12407
    Location:117192
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:253341
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:4122
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  26. XM_017023333.1XP_016878822.1  RNA binding protein fox-1 homolog 1 isoform X23

    UniProtKB/Swiss-Prot
    Q9NWB1
    Conserved Domains (3) summary
    cd12407
    Location:117192
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:253342
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:4122
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  27. XM_005255391.4XP_005255448.1  RNA binding protein fox-1 homolog 1 isoform X13

    See identical proteins and their annotated locations for XP_005255448.1

    Conserved Domains (4) summary
    PHA03193
    Location:45112
    PHA03193; tegument protein VP11/12; Provisional
    COG0724
    Location:100200
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:117192
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:253340
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  28. XM_017023342.1XP_016878831.1  RNA binding protein fox-1 homolog 1 isoform X41

  29. XM_017023338.1XP_016878827.1  RNA binding protein fox-1 homolog 1 isoform X36

    UniProtKB/Swiss-Prot
    Q9NWB1
    Conserved Domains (3) summary
    cd12407
    Location:117192
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:226315
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:4122
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
  30. XM_017023340.1XP_016878829.1  RNA binding protein fox-1 homolog 1 isoform X39

  31. XM_017023323.2XP_016878812.1  RNA binding protein fox-1 homolog 1 isoform X8

  32. XM_017023332.1XP_016878821.1  RNA binding protein fox-1 homolog 1 isoform X22

  33. XM_017023327.1XP_016878816.1  RNA binding protein fox-1 homolog 1 isoform X15

  34. XM_005255386.4XP_005255443.1  RNA binding protein fox-1 homolog 1 isoform X7

    Conserved Domains (4) summary
    PHA03193
    Location:70137
    PHA03193; tegument protein VP11/12; Provisional
    COG0724
    Location:125225
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:142217
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:278365
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  35. XM_017023337.1XP_016878826.1  RNA binding protein fox-1 homolog 1 isoform X35

  36. XM_017023334.1XP_016878823.1  RNA binding protein fox-1 homolog 1 isoform X24

  37. XM_024450308.1XP_024306076.1  RNA binding protein fox-1 homolog 1 isoform X28

    Conserved Domains (3) summary
    pfam12414
    Location:247336
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:142181
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl26247
    Location:38192
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  38. XM_011522547.2XP_011520849.1  RNA binding protein fox-1 homolog 1 isoform X25

    See identical proteins and their annotated locations for XP_011520849.1

    UniProtKB/TrEMBL
    X5D7T5
    Conserved Domains (3) summary
    cd12407
    Location:137212
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:273361
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:25208
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  39. XM_011522546.2XP_011520848.1  RNA binding protein fox-1 homolog 1 isoform X17

    See identical proteins and their annotated locations for XP_011520848.1

    UniProtKB/TrEMBL
    X5DNY3
    Related
    ENSP00000344196.4, ENST00000340209.8
    Conserved Domains (3) summary
    cd12407
    Location:137212
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:273362
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:25208
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  40. XM_005255387.4XP_005255444.1  RNA binding protein fox-1 homolog 1 isoform X9

    See identical proteins and their annotated locations for XP_005255444.1

    Conserved Domains (4) summary
    PHA03193
    Location:65132
    PHA03193; tegument protein VP11/12; Provisional
    COG0724
    Location:120220
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:137212
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:273360
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  41. XM_011522548.2XP_011520850.1  RNA binding protein fox-1 homolog 1 isoform X37

    See identical proteins and their annotated locations for XP_011520850.1

    UniProtKB/TrEMBL
    X5DP44
    Conserved Domains (3) summary
    cd12407
    Location:137212
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:246334
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:25208
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  42. XM_005255394.4XP_005255451.1  RNA binding protein fox-1 homolog 1 isoform X27

    See identical proteins and their annotated locations for XP_005255451.1

    Conserved Domains (3) summary
    cd12407
    Location:137212
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:246336
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:25208
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  43. XM_024450306.1XP_024306074.1  RNA binding protein fox-1 homolog 1 isoform X19

    Conserved Domains (3) summary
    pfam12414
    Location:242331
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:137176
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl26247
    Location:19187
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  44. XM_017023331.2XP_016878820.1  RNA binding protein fox-1 homolog 1 isoform X21

    Conserved Domains (4) summary
    PHA03193
    Location:2592
    PHA03193; tegument protein VP11/12; Provisional
    COG0724
    Location:80180
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:97172
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:233320
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  45. XM_024450315.1XP_024306083.1  RNA binding protein fox-1 homolog 1 isoform X40

    Conserved Domains (3) summary
    cd12407
    Location:97172
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:233321
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl27169
    Location:4102
    ZipA; ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
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