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Eif3i eukaryotic translation initiation factor 3, subunit I [ Mus musculus (house mouse) ]

Gene ID: 54709, updated on 8-Jan-2023

Summary

Official Symbol
Eif3iprovided by MGI
Official Full Name
eukaryotic translation initiation factor 3, subunit Iprovided by MGI
Primary source
MGI:MGI:1860763
See related
Ensembl:ENSMUSG00000028798 AllianceGenome:MGI:1860763
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
36kDa; Trip1; Eif3s2; D4Ertd632e
Summary
Contributes to translation initiation factor activity. Involved in translational initiation. Part of eukaryotic translation initiation factor 3 complex, eIF3m. Is expressed in embryo. Orthologous to human EIF3I (eukaryotic translation initiation factor 3 subunit I). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in genital fat pad adult (RPKM 152.6), liver E14.5 (RPKM 125.2) and 28 other tissues See more
Orthologs
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Genomic context

See Eif3i in Genome Data Viewer
Location:
4 D2.2; 4 63.26 cM
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (129485767..129494441, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (129591974..129600648, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene lymphocyte protein tyrosine kinase Neighboring gene microRNA 8119 Neighboring gene family with sequence similarity 167, member B Neighboring gene transmembrane protein 234 Neighboring gene doublecortin domain containing 2b Neighboring gene IQ motif containing C

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
contributes_to translation initiation factor activity IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to translation initiation factor activity ISO
Inferred from Sequence Orthology
more info
 
enables translation initiation factor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cytoplasmic translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translational initiation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in translational initiation ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
eukaryotic translation initiation factor 3 subunit I
Names
TGF-beta receptor binding protein
TGF-beta receptor-interacting protein 1
TRIP-1
eukaryotic translation initiation factor 3, subunit 1
eukaryotic translation initiation factor 3, subunit 2 (beta)
eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018799.2NP_061269.1  eukaryotic translation initiation factor 3 subunit I

    See identical proteins and their annotated locations for NP_061269.1

    Status: VALIDATED

    Source sequence(s)
    AK010781, BP769420, CJ079467
    Consensus CDS
    CCDS18698.1
    UniProtKB/Swiss-Prot
    Q9QZD9
    UniProtKB/TrEMBL
    A0A8C6MPG3
    Related
    ENSMUSP00000099653.5, ENSMUST00000102593.11
    Conserved Domains (3) summary
    COG2319
    Location:6311
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:1450
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:6311
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    129485767..129494441 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)