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ASNSD1 asparagine synthetase domain containing 1 [ Homo sapiens (human) ]

Gene ID: 54529, updated on 21-Dec-2019

Summary

Official Symbol
ASNSD1provided by HGNC
Official Full Name
asparagine synthetase domain containing 1provided by HGNC
Primary source
HGNC:HGNC:24910
See related
Ensembl:ENSG00000138381
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NS3TP1; NBLA00058
Expression
Ubiquitous expression in ovary (RPKM 15.1), placenta (RPKM 13.4) and 25 other tissues See more
Orthologs

Genomic context

See ASNSD1 in Genome Data Viewer
Location:
2q32.2
Exon count:
6
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (189661399..189670831)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (190526125..190535557)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene KDM3A pseudogene 1 Neighboring gene solute carrier family 40 member 1 Neighboring gene uncharacterized LOC105373793 Neighboring gene ASNSD1 upstream reading frame Neighboring gene ankyrin and armadillo repeat containing Neighboring gene OSGEPL1 antisense RNA 1 Neighboring gene O-sialoglycoprotein endopeptidase like 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20752

Gene Ontology Provided by GOA

Function Evidence Code Pubs
asparagine synthase (glutamine-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
asparagine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
biological_process ND
No biological Data available
more info
 
glutamine metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
asparagine synthetase domain-containing protein 1
Names
HCV NS3-transactivated protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001353497.1NP_001340426.1  asparagine synthetase domain-containing protein 1

    Status: VALIDATED

    Source sequence(s)
    AC012488
    Consensus CDS
    CCDS2300.1
    Related
    ENSP00000406790.1, ENST00000420250.1
    Conserved Domains (2) summary
    cd01991
    Location:322607
    Asn_Synthase_B_C; The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the ...
    cd03766
    Location:1179
    Gn_AT_II_novel; Gn_AT_II_novel. This asparagine synthase-related domain is present in eukaryotes but its function has not yet been determined. The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, ...
  2. NM_019048.4NP_061921.2  asparagine synthetase domain-containing protein 1

    Status: VALIDATED

    Source sequence(s)
    AC012488, AK000759, BC001243
    Consensus CDS
    CCDS2300.1
    Related
    ENSP00000260952.4, ENST00000260952.9
    Conserved Domains (2) summary
    cd01991
    Location:322607
    Asn_Synthase_B_C; The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the ...
    cd03766
    Location:1179
    Gn_AT_II_novel; Gn_AT_II_novel. This asparagine synthase-related domain is present in eukaryotes but its function has not yet been determined. The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    189661399..189670831
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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