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Asnsd1 asparagine synthetase domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 70396, updated on 26-Sep-2022

Summary

Official Symbol
Asnsd1provided by MGI
Official Full Name
asparagine synthetase domain containing 1provided by MGI
Primary source
MGI:MGI:1917646
See related
Ensembl:ENSMUSG00000026095 AllianceGenome:MGI:1917646
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2210409M21Rik
Summary
Is expressed in body cavity or lining; limb; tail; and vertebral axis musculature. Orthologous to human ASNSD1 (asparagine synthetase domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 29.7), CNS E11.5 (RPKM 15.1) and 22 other tissues See more
Orthologs
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Genomic context

See Asnsd1 in Genome Data Viewer
Location:
1; 1 C1.1
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (53383776..53391911, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (53344617..53352752, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene ORM1-like 1 (S. cerevisiae) Neighboring gene O-sialoglycoprotein endopeptidase-like 1 Neighboring gene ankyrin and armadillo repeat containing pseudogene Neighboring gene predicted gene, 50478 Neighboring gene predicted gene, 53553 Neighboring gene solute carrier family 39 (zinc transporter), member 10 pseudogene Neighboring gene dynein, axonemal, heavy chain 7A

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
asparagine synthetase domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290984.1NP_001277913.1  asparagine synthetase domain-containing protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001277913.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1. The encoded protein (isoform 2) is shorter than isoform 1.
    Source sequence(s)
    AA170909, AK168534
    Consensus CDS
    CCDS69888.1
    UniProtKB/TrEMBL
    Q3TGY6
    Related
    ENSMUSP00000139025.2, ENSMUST00000123519.9
    Conserved Domains (1) summary
    cd01991
    Location:5126
    Asn_Synthase_B_C; The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the ...
  2. NM_133728.3NP_598489.2  asparagine synthetase domain-containing protein 1 isoform 1

    See identical proteins and their annotated locations for NP_598489.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AA170909, AK031295, AK168534
    Consensus CDS
    CCDS14954.1
    UniProtKB/Swiss-Prot
    Q8BFS9, Q91YY3
    UniProtKB/TrEMBL
    Q3TGY6
    Related
    ENSMUSP00000027264.4, ENSMUST00000027264.10
    Conserved Domains (3) summary
    cd01991
    Location:322603
    Asn_Synthase_B_C; The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the ...
    cd03766
    Location:1179
    Gn_AT_II_novel; Gn_AT_II_novel. This asparagine synthase-related domain is present in eukaryotes but its function has not yet been determined. The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, ...
    TIGR01536
    Location:27599
    asn_synth_AEB; asparagine synthase (glutamine-hydrolyzing)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    53383776..53391911 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)