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PIMREG PICALM interacting mitotic regulator [ Homo sapiens (human) ]

Gene ID: 54478, updated on 12-Oct-2019

Summary

Official Symbol
PIMREGprovided by HGNC
Official Full Name
PICALM interacting mitotic regulatorprovided by HGNC
Primary source
HGNC:HGNC:25483
See related
Ensembl:ENSG00000129195 MIM:617611
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CATS; RCS1; FAM64A
Expression
Broad expression in spleen (RPKM 1.3), small intestine (RPKM 0.7) and 19 other tissues See more
Orthologs

Genomic context

See PIMREG in Genome Data Viewer
Location:
17p13.2
Exon count:
7
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (6444455..6451469)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (6347735..6354385)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371509 Neighboring gene uncharacterized LOC107985017 Neighboring gene aryl hydrocarbon receptor interacting protein like 1 Neighboring gene PITPNM family member 3 Neighboring gene KIAA0753 Neighboring gene RNA, 5S ribosomal pseudogene 435 Neighboring gene thioredoxin domain containing 17 Neighboring gene mediator complex subunit 31

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10156, FLJ10491

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
protein PIMREG
Names
CALM interacting protein expressed in thymus and spleen
CALM-interactor expressed in thymus and spleen
family with sequence similarity 64 member A
protein FAM64A
regulator of chromosome segregation 1
regulator of chromosome segregation protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195228.2NP_001182157.1  protein PIMREG isoform 2

    See identical proteins and their annotated locations for NP_001182157.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the 3' coding region, which results in a frameshift, compared to variant A. The resulting protein (isoform 2) is longer and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC055872, BC005004
    Consensus CDS
    CCDS56016.1
    UniProtKB/Swiss-Prot
    Q9BSJ6
    UniProtKB/TrEMBL
    A0A0S2Z5F0
    Related
    ENSP00000250056.8, ENST00000250056.12
    Conserved Domains (1) summary
    pfam07326
    Location:1232
    DUF1466; Protein of unknown function (DUF1466)
  2. NM_019013.3NP_061886.2  protein PIMREG isoform 1

    See identical proteins and their annotated locations for NP_061886.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the shorter isoform (1).
    Source sequence(s)
    AC055872, BC013966
    Consensus CDS
    CCDS32541.1
    UniProtKB/Swiss-Prot
    Q9BSJ6
    UniProtKB/TrEMBL
    A0A0S2Z5C7
    Related
    ENSP00000459235.1, ENST00000572447.6
    Conserved Domains (1) summary
    pfam07326
    Location:1231
    DUF1466; Protein of unknown function (DUF1466)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    6444455..6451469
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017024778.1XP_016880267.1  protein PIMREG isoform X1

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