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Pimreg PICALM interacting mitotic regulator [ Mus musculus (house mouse) ]

Gene ID: 109212, updated on 30-Apr-2024

Summary

Official Symbol
Pimregprovided by MGI
Official Full Name
PICALM interacting mitotic regulatorprovided by MGI
Primary source
MGI:MGI:1924434
See related
Ensembl:ENSMUSG00000020808 AllianceGenome:MGI:1924434
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CATS; Fam64a; 2610008F03Rik; 6720460F02Rik
Summary
Predicted to act upstream of or within cell division. Predicted to be located in nucleolus and nucleoplasm. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; integumental system; and limb. Orthologous to human PIMREG (PICALM interacting mitotic regulator). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E11.5 (RPKM 26.3), limb E14.5 (RPKM 16.9) and 10 other tissues See more
Orthologs
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Genomic context

See Pimreg in Genome Data Viewer
Location:
11 B4; 11 43.81 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (71932867..71938197)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (72042428..72047372)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46262 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:71809517-71809670 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:71809714-71809823 Neighboring gene predicted gene, 23226 Neighboring gene STARR-positive B cell enhancer ABC_E9825 Neighboring gene STARR-positive B cell enhancer ABC_E8421 Neighboring gene aryl hydrocarbon receptor-interacting protein-like 1 Neighboring gene PITPNM family member 3 Neighboring gene predicted gene, 46286 Neighboring gene STARR-seq mESC enhancer starr_29899 Neighboring gene RIKEN cDNA 4933427D14 gene Neighboring gene predicted gene, 57849

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein PIMREG
Names
CALM-interactor expressed in thymus and spleen homolog
family with sequence similarity 64, member A
protein FAM64A
regulator of chromosome segregation protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418158.1NP_001405087.1  protein PIMREG

    Status: VALIDATED

    Source sequence(s)
    BX119911
    UniProtKB/Swiss-Prot
    Q8BFY7, Q8K2Z7
  2. NM_001418159.1NP_001405088.1  protein PIMREG

    Status: VALIDATED

    Source sequence(s)
    BX119911
    UniProtKB/Swiss-Prot
    Q8BFY7, Q8K2Z7
  3. NM_144526.4NP_653109.2  protein PIMREG

    See identical proteins and their annotated locations for NP_653109.2

    Status: VALIDATED

    Source sequence(s)
    BX119911
    Consensus CDS
    CCDS48840.1
    UniProtKB/Swiss-Prot
    Q8BFY7, Q8K2Z7
    UniProtKB/TrEMBL
    Q8VDW8
    Related
    ENSMUSP00000021164.4, ENSMUST00000021164.4
    Conserved Domains (1) summary
    pfam07326
    Location:1221
    DUF1466; Protein of unknown function (DUF1466)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    71932867..71938197
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)