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Rpp30 ribonuclease P/MRP 30 subunit [ Mus musculus (house mouse) ]

Gene ID: 54364, updated on 11-Apr-2024

Summary

Official Symbol
Rpp30provided by MGI
Official Full Name
ribonuclease P/MRP 30 subunitprovided by MGI
Primary source
MGI:MGI:1859683
See related
Ensembl:ENSMUSG00000024800 AllianceGenome:MGI:1859683
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TSG15; Rnasep2
Summary
Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in RNA phosphodiester bond hydrolysis, endonucleolytic and tRNA 5'-leader removal. Predicted to act upstream of or within rRNA processing. Predicted to be located in nucleus. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Is expressed in several structures, including alimentary system; brain ventricular layer; olfactory epithelium; seminiferous cord; and vibrissa. Orthologous to human RPP30 (ribonuclease P/MRP subunit p30). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 13.6), liver E14 (RPKM 10.6) and 20 other tissues See more
Orthologs
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Genomic context

See Rpp30 in Genome Data Viewer
Location:
19 C2; 19 30.41 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (36061118..36082173)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (36083689..36104773)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A830019P07 gene Neighboring gene peroxiredoxin 3 pseudogene Neighboring gene STARR-seq mESC enhancer starr_46016 Neighboring gene STARR-seq mESC enhancer starr_46017 Neighboring gene STARR-seq mESC enhancer starr_46018 Neighboring gene STARR-seq mESC enhancer starr_46019 Neighboring gene STARR-seq mESC enhancer starr_46020 Neighboring gene 5-hydroxytryptamine (serotonin) receptor 7 Neighboring gene STARR-positive B cell enhancer ABC_E7647 Neighboring gene STARR-positive B cell enhancer ABC_E5699 Neighboring gene ankyrin repeat domain 1 Neighboring gene predicted gene, 32081 Neighboring gene predicted gene, 32027

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ribonuclease P RNA binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to ribonuclease P activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within rRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in tRNA 5'-leader removal ISO
Inferred from Sequence Orthology
more info
 
involved_in tRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of multimeric ribonuclease P complex ISO
Inferred from Sequence Orthology
more info
 
part_of nucleolar ribonuclease P complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of ribonuclease MRP complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ribonuclease P protein subunit p30
Names
RNase P subunit 2
RNaseP protein p30
ribonuclease P/MRP 30kDa subunit
ribonuclease P2
NP_062301.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019428.4NP_062301.3  ribonuclease P protein subunit p30

    See identical proteins and their annotated locations for NP_062301.3

    Status: VALIDATED

    Source sequence(s)
    AC119234
    Consensus CDS
    CCDS29770.1
    UniProtKB/Swiss-Prot
    O88796
    UniProtKB/TrEMBL
    Q6P6M0
    Related
    ENSMUSP00000025714.8, ENSMUST00000025714.9
    Conserved Domains (1) summary
    pfam01876
    Location:21224
    RNase_P_p30; RNase P subunit p30

RNA

  1. NR_182659.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC119234

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    36061118..36082173
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)