Rpp30 ribonuclease P/MRP 30 subunit [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rpp30provided by MGI
Official Full Name: ribonuclease P/MRP 30 subunitprovided by MGI
Primary source: MGI:MGI:1859683
See related: Ensembl:ENSMUSG00000024800 AllianceGenome:MGI:1859683
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: TSG15; Rnasep2
Summary: Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in RNA phosphodiester bond hydrolysis, endonucleolytic and tRNA 5'-leader removal. Predicted to act upstream of or within rRNA processing. Predicted to be located in nucleus. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Is expressed in several structures, including alimentary system; brain ventricular layer; olfactory epithelium; seminiferous cord; and vibrissa. Orthologous to human RPP30 (ribonuclease P/MRP subunit p30). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in CNS E11.5 (RPKM 13.6), liver E14 (RPKM 10.6) and 20 other tissues See more
Orthologs: human all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 19; 19 C2

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	19	NC_000085.7 (36061089..36082173)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	19	NC_000085.6 (36083689..36104773)

Chromosome 19 - NC_000085.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

RH127064 (e-PCR)
- UniSTS:209461

U95123 (e-PCR)
- UniSTS:160827

Homology

Homologs of the Rpp30 gene: The Rpp30 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, and frog.
Orthologs from Annotation Pipeline: 484 organisms have orthologs with human gene Rpp30
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info	PubMed
enables ribonuclease P RNA binding	ISO Inferred from Sequence Orthology more info
contributes_to ribonuclease P activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in RNA phosphodiester bond hydrolysis, endonucleolytic	IBA Inferred from Biological aspect of Ancestor more info	PubMed
acts_upstream_of_or_within rRNA processing	IEA Inferred from Electronic Annotation more info
involved_in tRNA 5'-leader removal	ISO Inferred from Sequence Orthology more info
involved_in tRNA processing	IBA Inferred from Biological aspect of Ancestor more info	PubMed

Component	Evidence Code	Pubs
part_of multimeric ribonuclease P complex	ISO Inferred from Sequence Orthology more info
part_of nucleolar ribonuclease P complex	IBA Inferred from Biological aspect of Ancestor more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of ribonuclease MRP complex	ISO Inferred from Sequence Orthology more info

General protein information

Go to the top of the page Help

Preferred Names: ribonuclease P protein subunit p30

Names: RNase P subunit 2; RNaseP protein p30; ribonuclease P/MRP 30kDa subunit; ribonuclease P2

NP_062301.3

EC 3.1.26.5

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.