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UBL3 ubiquitin like 3 [ Homo sapiens (human) ]

Gene ID: 5412, updated on 5-Jul-2025
Official Symbol
UBL3provided by HGNC
Official Full Name
ubiquitin like 3provided by HGNC
Primary source
HGNC:HGNC:12504
See related
Ensembl:ENSG00000122042 MIM:604711; AllianceGenome:HGNC:12504
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HCG-1; PNSC1
Summary
Located in extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025]
Expression
Ubiquitous expression in brain (RPKM 38.2), stomach (RPKM 32.6) and 25 other tissues See more
Orthologs
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See UBL3 in Genome Data Viewer
Location:
13q12.3
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (29764371..29850617, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (28987070..29073260, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (30338508..30424754, complement)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102723345 Neighboring gene uncharacterized LOC105370139 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr13:30276622-30277821 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7522 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5223 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7523 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7524 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7525 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5224 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7526 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5225 Neighboring gene ReSE screen-validated silencer GRCh37_chr13:30445927-30446158 Neighboring gene translocase of inner mitochondrial membrane 8B pseudogene 1 Neighboring gene long intergenic non-protein coding RNA 297

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

EBI GWAS Catalog

Description
A genome-wide association study for reading and language abilities in two population cohorts.
EBI GWAS Catalog
Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2.
EBI GWAS Catalog
Products Interactant Other Gene Complex Source Pubs Description

Markers

Clone Names

  • FLJ32018, DKFZp434K151

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular exosome HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
ubiquitin-like protein 3
Names
MUB
hsMUB
membrane-anchored ubiquitin-fold protein
protein HCG-1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007106.4NP_009037.1  ubiquitin-like protein 3

    See identical proteins and their annotated locations for NP_009037.1

    Status: VALIDATED

    Source sequence(s)
    AK311846, AL080177, AL158193, BM453277, DA246318, DA400786
    Consensus CDS
    CCDS9334.1
    UniProtKB/Swiss-Prot
    B2R4J1, O95164, Q5RL72, Q5VZS0, Q6FIG8, Q96SG7
    Related
    ENSP00000370055.4, ENST00000380680.5
    Conserved Domains (1) summary
    cd17048
    Location:1091
    Ubl_UBL3; ubiquitin-like (Ubl) domain found in ubiquitin-like protein 3 (UBL3) and similar proteins

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    29764371..29850617 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047430394.1XP_047286350.1  ubiquitin-like protein 3 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    28987070..29073260 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)