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Ubl3 ubiquitin-like 3 [ Mus musculus (house mouse) ]

Gene ID: 24109, updated on 4-Dec-2022

Summary

Official Symbol
Ubl3provided by MGI
Official Full Name
ubiquitin-like 3provided by MGI
Primary source
MGI:MGI:1344373
See related
Ensembl:ENSMUSG00000001687 AllianceGenome:MGI:1344373
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
HCG; MUB; mmMUB
Summary
Predicted to be located in plasma membrane. Orthologous to human UBL3 (ubiquitin like 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 50.1), cerebellum adult (RPKM 42.3) and 28 other tissues See more
Orthologs
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Genomic context

See Ubl3 in Genome Data Viewer
Location:
5; 5 G3
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (148441441..148489689, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (148504631..148552879, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene microtubule associated tumor suppressor candidate 2 Neighboring gene fused in sarcoma pseudogene Neighboring gene solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 Neighboring gene predicted gene, 35735 Neighboring gene predicted gene, 35994 Neighboring gene predicted gene, 35929

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ubiquitin-like protein 3
Names
membrane-anchored ubiquitin-fold protein
protein HCG-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001359199.1NP_001346128.1  ubiquitin-like protein 3 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AC157990, AC158302
    Consensus CDS
    CCDS39403.1
    UniProtKB/Swiss-Prot
    Q3UKM1
    UniProtKB/TrEMBL
    A0A6P5PUE2, A0A8C6HVG7
    Related
    ENSMUSP00000131049.2, ENSMUST00000164904.2
    Conserved Domains (1) summary
    cd17048
    Location:1091
    Ubl_UBL3; ubiquitin-like (Ubl) domain found in ubiquitin-like protein 3 (UBL3) and similar proteins
  2. NM_001359200.1NP_001346129.1  ubiquitin-like protein 3 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 3, 4, and 5 all encode the same isoform (b).
    Source sequence(s)
    AC157990, CA574503
    Conserved Domains (1) summary
    cl28922
    Location:147
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  3. NM_001359201.1NP_001346130.1  ubiquitin-like protein 3 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 3, 4, and 5 all encode the same isoform (b).
    Source sequence(s)
    AC157990, AC158302
    Conserved Domains (1) summary
    cl28922
    Location:147
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  4. NM_001359202.1NP_001346131.1  ubiquitin-like protein 3 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 3, 4, and 5 all encode the same isoform (b).
    Source sequence(s)
    AC157990, AC158302
    Conserved Domains (1) summary
    cl28922
    Location:147
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  5. NM_011908.2NP_036038.1  ubiquitin-like protein 3 isoform a

    See identical proteins and their annotated locations for NP_036038.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AK145952, AV226728, BU059122, CK794503, DV661495
    Consensus CDS
    CCDS39403.1
    UniProtKB/Swiss-Prot
    Q3UKM1, Q9Z2M6
    UniProtKB/TrEMBL
    A0A6P5PUE2, A0A8C6HVG7
    Related
    ENSMUSP00000078303.8, ENSMUST00000079324.14
    Conserved Domains (1) summary
    cd17048
    Location:1091
    Ubl_UBL3; ubiquitin-like (Ubl) domain found in ubiquitin-like protein 3 (UBL3) and similar proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    148441441..148489689 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006504832.4XP_006504895.1  ubiquitin-like protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006504895.1

    UniProtKB/Swiss-Prot
    Q3UKM1, Q9Z2M6
    UniProtKB/TrEMBL
    A0A6P5PUE2, A0A8C6HVG7
    Related
    ENSMUSP00000144073.2, ENSMUST00000201595.4
    Conserved Domains (1) summary
    cd17048
    Location:1091
    Ubl_UBL3; ubiquitin-like (Ubl) domain found in ubiquitin-like protein 3 (UBL3) and similar proteins