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DHX57 DExH-box helicase 57 [ Bos taurus (domestic cattle) ]

Gene ID: 540993, updated on 17-Aug-2024

Summary

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Official Symbol
DHX57provided by VGNC
Official Full Name
DExH-box helicase 57provided by VGNC
Primary source
VGNC:VGNC:28057
See related
BGD:BT10262; Ensembl:ENSBTAG00000014679
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (21145280..21205639, complement)

Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat protein 39B-like Neighboring gene gem nuclear organelle associated protein 6 Neighboring gene uncharacterized LOC132346555 Neighboring gene MORN repeat containing 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
  2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in intracellular anatomical structure IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
putative ATP-dependent RNA helicase DHX57
Names
DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DEAH-box helicase 57
NP_001192980.1
XP_005212723.1
XP_005212724.1
XP_024854845.1
XP_059747428.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001206051.3 → NP_001192980.1  putative ATP-dependent RNA helicase DHX57

    See identical proteins and their annotated locations for NP_001192980.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000011
    UniProtKB/TrEMBL
    F1N1A2
    Related
    ENSBTAP00000019540.7, ENSBTAT00000019540.7
    Conserved Domains (8) summary
    smart00356
    Location:298 → 318
    ZnF_C3H1; zinc finger
    smart00487
    Location:549 → 726
    DEXDc; DEAD-like helicases superfamily
    smart00847
    Location:1039 → 1121
    HA2; Helicase associated domain (HA2) Add an annotation
    cd00046
    Location:557 → 699
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd14317
    Location:176 → 213
    UBA_DHX57; UBA domain found in putative ATP-dependent RNA helicase DHX57 and similar proteins
    pfam00271
    Location:828 → 964
    Helicase_C; Helicase conserved C-terminal domain
    pfam05773
    Location:238 → 413
    RWD; RWD domain
    pfam07717
    Location:1160 → 1307
    OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    21145280..21205639 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024999077.2 → XP_024854845.1  putative ATP-dependent RNA helicase DHX57 isoform X2

    UniProtKB/TrEMBL
    F1N1A2
    Conserved Domains (3) summary
    COG1643
    Location:495 → 1371
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
    cd14317
    Location:175 → 212
    UBA_DHX57; UBA domain found in putative ATP-dependent RNA helicase DHX57 and similar proteins
    pfam05773
    Location:240 → 413
    RWD; RWD domain

  2. XM_005212666.5 → XP_005212723.1  putative ATP-dependent RNA helicase DHX57 isoform X1

    See identical proteins and their annotated locations for XP_005212723.1

    UniProtKB/TrEMBL
    F1N1A2
    Conserved Domains (8) summary
    smart00356
    Location:298 → 318
    ZnF_C3H1; zinc finger
    smart00487
    Location:549 → 726
    DEXDc; DEAD-like helicases superfamily
    smart00847
    Location:1039 → 1121
    HA2; Helicase associated domain (HA2) Add an annotation
    cd00046
    Location:557 → 699
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd14317
    Location:176 → 213
    UBA_DHX57; UBA domain found in putative ATP-dependent RNA helicase DHX57 and similar proteins
    pfam00271
    Location:828 → 964
    Helicase_C; Helicase conserved C-terminal domain
    pfam05773
    Location:238 → 413
    RWD; RWD domain
    pfam07717
    Location:1160 → 1307
    OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold

  3. XM_005212667.5 → XP_005212724.1  putative ATP-dependent RNA helicase DHX57 isoform X1

    See identical proteins and their annotated locations for XP_005212724.1

    UniProtKB/TrEMBL
    F1N1A2
    Conserved Domains (8) summary
    smart00356
    Location:298 → 318
    ZnF_C3H1; zinc finger
    smart00487
    Location:549 → 726
    DEXDc; DEAD-like helicases superfamily
    smart00847
    Location:1039 → 1121
    HA2; Helicase associated domain (HA2) Add an annotation
    cd00046
    Location:557 → 699
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd14317
    Location:176 → 213
    UBA_DHX57; UBA domain found in putative ATP-dependent RNA helicase DHX57 and similar proteins
    pfam00271
    Location:828 → 964
    Helicase_C; Helicase conserved C-terminal domain
    pfam05773
    Location:238 → 413
    RWD; RWD domain
    pfam07717
    Location:1160 → 1307
    OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold

  4. XM_059891445.1 → XP_059747428.1  putative ATP-dependent RNA helicase DHX57 isoform X3

    UniProtKB/TrEMBL
    A0AAA9T2M0, A0AAA9TJM0
    Related
    ENSBTAP00000090884.1, ENSBTAT00000109623.1

RNA

  1. XR_009496295.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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Molecular Biology Databases
Research Materials