U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LEF1 lymphoid enhancer binding factor 1 [ Bos taurus (cattle) ]

Gene ID: 535399, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
LEF1provided by VGNC
Official Full Name
lymphoid enhancer binding factor 1provided by VGNC
Primary source
VGNC:VGNC:30833
See related
BGD:BT23252; Ensembl:ENSBTAG00000006844
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 6
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (17083384..17200676)

Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L34 Neighboring gene uncharacterized LOC132345477 Neighboring gene uncharacterized LOC132345570 Neighboring gene hydroxyacyl-CoA dehydrogenase Neighboring gene cytochrome P450 family 2 subfamily U member 1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of beta-catenin-TCF complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
lymphoid enhancer-binding factor 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001192856.1 → NP_001179785.1  lymphoid enhancer-binding factor 1

    See identical proteins and their annotated locations for NP_001179785.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000006
    UniProtKB/TrEMBL
    E1BJ93
    Related
    ENSBTAP00000008991.5, ENSBTAT00000008991.7
    Conserved Domains (2) summary
    cd01388
    Location:298 → 369
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 213
    CTNNB1_binding; N-terminal CTNNB1 binding

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    17083384..17200676
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005207653.5 → XP_005207710.1  lymphoid enhancer-binding factor 1 isoform X1

    See identical proteins and their annotated locations for XP_005207710.1

    UniProtKB/TrEMBL
    A0A3Q1MZ99
    Related
    ENSBTAP00000061494.1, ENSBTAT00000068676.2
    Conserved Domains (2) summary
    cd01388
    Location:298 → 369
    SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
    pfam08347
    Location:1 → 213
    CTNNB1_binding; N-terminal CTNNB1 binding

  2. XM_005207654.5 → XP_005207711.1  lymphoid enhancer-binding factor 1 isoform X2

    See identical proteins and their annotated locations for XP_005207711.1

    UniProtKB/TrEMBL
    A0A3Q1MAH2
    Related
    ENSBTAP00000071015.1, ENSBTAT00000067746.2
    Conserved Domains (2) summary
    cd01388
    Location:270 → 341
    SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
    pfam08347
    Location:1 → 213
    CTNNB1_binding; N-terminal CTNNB1 binding

  3. XM_005207655.5 → XP_005207712.1  lymphoid enhancer-binding factor 1 isoform X3

    See identical proteins and their annotated locations for XP_005207712.1

    Conserved Domains (2) summary
    cd01388
    Location:270 → 341
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 213
    CTNNB1_binding; N-terminal CTNNB1 binding

  4. XM_005207656.5 → XP_005207713.1  lymphoid enhancer-binding factor 1 isoform X5

    See identical proteins and their annotated locations for XP_005207713.1

    Conserved Domains (2) summary
    cd01388
    Location:230 → 301
    SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
    pfam08347
    Location:6 → 145
    CTNNB1_binding; N-terminal CTNNB1 binding

  5. XM_024993309.2 → XP_024849077.1  lymphoid enhancer-binding factor 1 isoform X4

    Conserved Domains (2) summary
    cd01388
    Location:241 → 312
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:14 → 156
    CTNNB1_binding; N-terminal CTNNB1 binding

  6. XM_005207657.5 → XP_005207714.1  lymphoid enhancer-binding factor 1 isoform X7

    See identical proteins and their annotated locations for XP_005207714.1

    Related
    ENSBTAP00000079451.1, ENSBTAT00000107434.1
    Conserved Domains (2) summary
    cd01388
    Location:230 → 301
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:6 → 145
    CTNNB1_binding; N-terminal CTNNB1 binding

  7. XM_059887573.1 → XP_059743556.1  lymphoid enhancer-binding factor 1 isoform X6

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.