U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tsnax translin-associated factor X [ Mus musculus (house mouse) ]

Gene ID: 53424, updated on 2-May-2024

Summary

Official Symbol
Tsnaxprovided by MGI
Official Full Name
translin-associated factor Xprovided by MGI
Primary source
MGI:MGI:1855672
See related
Ensembl:ENSMUSG00000056820 AllianceGenome:MGI:1855672
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Trax
Summary
Predicted to enable A2A adenosine receptor binding activity; RNA binding activity; and endoribonuclease activity. Predicted to contribute to sequence-specific DNA binding activity and single-stranded DNA binding activity. Predicted to act upstream of or within cell differentiation and spermatogenesis. Located in cytoplasm. Is expressed in several structures, including body cavity or lining; genitourinary system; respiratory system; tail; and vertebral axis musculature. Orthologous to human TSNAX (translin associated factor X). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in cortex adult (RPKM 51.2), CNS E18 (RPKM 49.9) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Tsnax in Genome Data Viewer
Location:
8 E2; 8 73.1 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (125739780..125760947)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (125013041..125034208)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene egl-9 family hypoxia-inducible factor 1 Neighboring gene predicted gene, 46060 Neighboring gene predicted gene, 39281 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:127536767-127536876 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:127591083-127591270 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:127591569-127591752 Neighboring gene VISTA enhancer mm1749 Neighboring gene disrupted in schizophrenia 1 Neighboring gene VISTA enhancer mm149 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:127817421-127817530 Neighboring gene STARR-seq mESC enhancer starr_23015 Neighboring gene STARR-seq mESC enhancer starr_23016 Neighboring gene STARR-seq mESC enhancer starr_23018 Neighboring gene predicted gene, 30713

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (5)  1 citation
  • Gene trapped (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables A2A adenosine receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA endonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to single-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
involved_in regulatory ncRNA-mediated post-transcriptional gene silencing NAS
Non-traceable Author Statement
more info
PubMed 
involved_in siRNA processing ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
part_of endoribonuclease complex ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
translin-associated protein X

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016909.3NP_058605.1  translin-associated protein X

    See identical proteins and their annotated locations for NP_058605.1

    Status: VALIDATED

    Source sequence(s)
    AL672234
    Consensus CDS
    CCDS22778.1
    UniProtKB/Swiss-Prot
    Q3UJR2, Q9QZE7
    UniProtKB/TrEMBL
    Q3TXK6
    Related
    ENSMUSP00000075290.7, ENSMUST00000075896.7
    Conserved Domains (1) summary
    cl00957
    Location:42256
    Translin-like; Translin and translin-associated factor-X (TRAX)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    125739780..125760947
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)