U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Exoc7 exocyst complex component 7 [ Mus musculus (house mouse) ]

Gene ID: 53413, updated on 11-Apr-2024

Summary

Official Symbol
Exoc7provided by MGI
Official Full Name
exocyst complex component 7provided by MGI
Primary source
MGI:MGI:1859270
See related
Ensembl:ENSMUSG00000020792 AllianceGenome:MGI:1859270
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Exo70; sec70
Summary
Involved in protein localization to ciliary membrane. Located in growth cone membrane. Is active in ciliary basal body. Is expressed in thymus primordium. Orthologous to human EXOC7 (exocyst complex component 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 16.9), CNS E14 (RPKM 16.2) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Exoc7 in Genome Data Viewer
Location:
11 E2; 11 81.11 cM
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (116178823..116197574, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (116287997..116306750, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene signal recognition particle 68 Neighboring gene STARR-positive B cell enhancer ABC_E9847 Neighboring gene galanin receptor 2 Neighboring gene STARR-positive B cell enhancer ABC_E7099 Neighboring gene predicted gene, 26730 Neighboring gene STARR-seq mESC enhancer starr_31197 Neighboring gene STARR-seq mESC enhancer starr_31198 Neighboring gene forkhead box J1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables phosphatidylinositol-4,5-bisphosphate binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein-macromolecule adaptor activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in centriolar satellite ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
part_of exocyst IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of exocyst NAS
Non-traceable Author Statement
more info
PubMed 
located_in growth cone membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule organizing center ISO
Inferred from Sequence Orthology
more info
 
is_active_in midbody ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
exocyst complex component 7
Names
exocyst complex component Exo70
exocyst component protein 70 kDa homolog

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001162872.3NP_001156344.1  exocyst complex component 7 isoform 2

    See identical proteins and their annotated locations for NP_001156344.1

    Status: VALIDATED

    Source sequence(s)
    AL645861
    Consensus CDS
    CCDS48983.1
    UniProtKB/TrEMBL
    Q3TIP4, Q542L0, Q7TPT3
    Related
    ENSMUSP00000102019.4, ENSMUST00000106411.10
    Conserved Domains (1) summary
    pfam03081
    Location:288647
    Exo70; Exo70 exocyst complex subunit
  2. NM_001347636.3NP_001334565.1  exocyst complex component 7 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL645861
    Consensus CDS
    CCDS83935.1
    UniProtKB/TrEMBL
    A2AAN0, Q3TIP4, Q7TPT3
    Related
    ENSMUSP00000102021.4, ENSMUST00000106413.10
  3. NM_001362838.2NP_001349767.1  exocyst complex component 7 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL645861
    UniProtKB/TrEMBL
    Q69ZS4
    Conserved Domains (1) summary
    pfam03081
    Location:342714
    Exo70; Exo70 exocyst complex subunit
  4. NM_001362839.2NP_001349768.1  exocyst complex component 7 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AL645861
    UniProtKB/TrEMBL
    Q3TIP4, Q7TPT3
    Conserved Domains (1) summary
    pfam03081
    Location:288660
    Exo70; Exo70 exocyst complex subunit
  5. NM_001378960.1NP_001365889.1  exocyst complex component 7 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AL645861
    UniProtKB/TrEMBL
    Q3TIP4, Q7TPT3
    Related
    ENSMUST00000139699.8
    Conserved Domains (1) summary
    pfam03081
    Location:336701
    Exo70; Exo70 exocyst complex subunit
  6. NM_001378961.1NP_001365890.1  exocyst complex component 7 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AL645861
    UniProtKB/TrEMBL
    Q3TIP4, Q7TPT3
    Conserved Domains (1) summary
    pfam03081
    Location:305670
    Exo70; Exo70 exocyst complex subunit
  7. NM_016857.4NP_058553.2  exocyst complex component 7 isoform 1

    See identical proteins and their annotated locations for NP_058553.2

    Status: VALIDATED

    Source sequence(s)
    AL645861
    Consensus CDS
    CCDS25664.1
    UniProtKB/Swiss-Prot
    O35250, Q8K121
    UniProtKB/TrEMBL
    Q3USE0, Q69ZS4
    Related
    ENSMUSP00000021147.8, ENSMUST00000021147.14
    Conserved Domains (1) summary
    pfam03081
    Location:313691
    Exo70; Exo70 exocyst complex subunit

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    116178823..116197574 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006533734.4XP_006533797.1  exocyst complex component 7 isoform X1

    UniProtKB/TrEMBL
    Q69ZS4
    Conserved Domains (1) summary
    pfam03081
    Location:305683
    Exo70; Exo70 exocyst complex subunit