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Banp BTG3 associated nuclear protein [ Mus musculus (house mouse) ]

Gene ID: 53325, updated on 3-Apr-2024

Summary

Official Symbol
Banpprovided by MGI
Official Full Name
BTG3 associated nuclear proteinprovided by MGI
Primary source
MGI:MGI:1889023
See related
Ensembl:ENSMUSG00000025316 AllianceGenome:MGI:1889023
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SMAR1
Summary
Enables p53 binding activity. Involved in positive regulation of transcription, DNA-templated. Acts upstream of or within negative regulation of protein catabolic process and protein localization to nucleus. Located in nucleus. Is expressed in bladder; heart; musculature; spleen; and thymus. Orthologous to human BANP (BTG3 associated nuclear protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 15.5), thymus adult (RPKM 13.6) and 28 other tissues See more
Orthologs
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Genomic context

See Banp in Genome Data Viewer
Location:
8 E1; 8 70.82 cM
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (122674711..122755999)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (121947972..122029260)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9121 Neighboring gene STARR-positive B cell enhancer ABC_E8267 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:124432414-124432597 Neighboring gene solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 Neighboring gene cDNA sequence BC048644 Neighboring gene carbonic anhydrase 5a, mitochondrial Neighboring gene predicted gene, 27011 Neighboring gene ornithine decarboxylase, structural 1 pseudogene Neighboring gene microRNA 7237 Neighboring gene zinc finger protein 469 Neighboring gene STARR-seq mESC enhancer starr_22941 Neighboring gene predicted gene, 34413 Neighboring gene STARR-seq mESC enhancer starr_22942 Neighboring gene predicted gene, 39268

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (4) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables p53 binding IDA
Inferred from Direct Assay
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
protein BANP
Names
scaffold/matrix-associated region-1-binding protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110100.2NP_001103570.1  protein BANP isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) uses an alternate splice site in the coding region compared to variant 2. The resulting protein (isoform 1) is shorter but has the same N- and C-termini compared to isoform 2.
    Source sequence(s)
    AC116772, BC062641, CX207431, DV661446
    UniProtKB/Swiss-Prot
    Q8VBU8
    Conserved Domains (1) summary
    smart01025
    Location:257330
    BEN; The BEN domain is found in diverse animal proteins
  2. NM_001285981.1NP_001272910.1  protein BANP isoform 3

    See identical proteins and their annotated locations for NP_001272910.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon in the coding region compared to variant 2. The resulting protein (isoform 3) is shorter but has the same N- and C-termini compared to isoform 2.
    Source sequence(s)
    AC116772, BC062641, CX207431
    Consensus CDS
    CCDS72176.1
    UniProtKB/Swiss-Prot
    Q8VBU8
    Related
    ENSMUSP00000026354.9, ENSMUST00000026354.15
    Conserved Domains (1) summary
    smart01025
    Location:218291
    BEN; The BEN domain is found in diverse animal proteins
  3. NM_001285983.1NP_001272912.1  protein BANP isoform 4

    See identical proteins and their annotated locations for NP_001272912.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate in-frame exon and uses an alternate splice site in the coding region compared to variant 2. The resulting protein (isoform 4) is shorter but has the same N- and C-termini compared to isoform 2.
    Source sequence(s)
    AC116772, AF235503, CX207431, DV661446
    Consensus CDS
    CCDS72177.1
    UniProtKB/Swiss-Prot
    Q8VBU8
    Related
    ENSMUSP00000090766.7, ENSMUST00000093078.13
    Conserved Domains (1) summary
    smart01025
    Location:218291
    BEN; The BEN domain is found in diverse animal proteins
  4. NM_001413724.1NP_001400653.1  protein BANP isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC116772
  5. NM_001413725.1NP_001400654.1  protein BANP isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC116772
  6. NM_001413726.1NP_001400655.1  protein BANP isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC116772
  7. NM_001413727.1NP_001400656.1  protein BANP isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC116772
  8. NM_001413728.1NP_001400657.1  protein BANP isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC116772
  9. NM_001413729.1NP_001400658.1  protein BANP isoform 10

    Status: VALIDATED

    Source sequence(s)
    AC116772
  10. NM_001413730.1NP_001400659.1  protein BANP isoform 10

    Status: VALIDATED

    Source sequence(s)
    AC116772
  11. NM_001413731.1NP_001400660.1  protein BANP isoform 11

    Status: VALIDATED

    Source sequence(s)
    AC116772
    Related
    ENSMUSP00000132434.3, ENSMUST00000167711.9
  12. NM_016812.4NP_058092.2  protein BANP isoform 2

    See identical proteins and their annotated locations for NP_058092.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents the longest transcript and encodes the longest protein (isoform 2).
    Source sequence(s)
    AC116772, BC062641, CX207431
    Consensus CDS
    CCDS40502.1
    UniProtKB/Swiss-Prot
    O88973, Q3U4R5, Q8VBU8, Q91YZ1, Q9ES51
    Related
    ENSMUSP00000132095.2, ENSMUST00000170857.8
    Conserved Domains (1) summary
    smart01025
    Location:257330
    BEN; The BEN domain is found in diverse animal proteins

RNA

  1. NR_182207.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC116772
  2. NR_182208.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC116772

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    122674711..122755999
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017312899.2XP_017168388.1  protein BANP isoform X1

    UniProtKB/Swiss-Prot
    O88973, Q3U4R5, Q8VBU8, Q91YZ1, Q9ES51
    Conserved Domains (1) summary
    smart01025
    Location:257330
    BEN; The BEN domain is found in diverse animal proteins
  2. XM_011248442.1XP_011246744.1  protein BANP isoform X2

    UniProtKB/Swiss-Prot
    Q8VBU8
    Related
    ENSMUSP00000133783.2, ENSMUST00000173254.8
    Conserved Domains (1) summary
    smart01025
    Location:257330
    BEN; The BEN domain is found in diverse animal proteins
  3. XM_030243675.2XP_030099535.1  protein BANP isoform X6

    Conserved Domains (1) summary
    smart01025
    Location:116189
    BEN; The BEN domain is found in diverse animal proteins
  4. XM_030243674.2XP_030099534.1  protein BANP isoform X5

    Conserved Domains (1) summary
    smart01025
    Location:116189
    BEN; The BEN domain is found in diverse animal proteins
  5. XM_011248445.1XP_011246747.1  protein BANP isoform X7

    UniProtKB/TrEMBL
    F6V6B6
    Conserved Domains (1) summary
    smart01025
    Location:2396
    BEN; The BEN domain is found in diverse animal proteins