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Ppp1r10 protein phosphatase 1, regulatory subunit 10 [ Mus musculus (house mouse) ]

Gene ID: 52040, updated on 14-Aug-2019

Summary

Official Symbol
Ppp1r10provided by MGI
Official Full Name
protein phosphatase 1, regulatory subunit 10provided by MGI
Primary source
MGI:MGI:1289273
See related
Ensembl:ENSMUSG00000039220
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fb19; Cat53; Pnuts; D17Ertd808e; 2610025H06Rik
Expression
Ubiquitous expression in testis adult (RPKM 26.6), thymus adult (RPKM 16.2) and 28 other tissues See more
Orthologs

Genomic context

See Ppp1r10 in Genome Data Viewer
Location:
17 B1; 17 18.77 cM
Exon count:
23
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (35916512..35932283)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (36053856..36069228)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene alpha tubulin acetyltransferase 1 Neighboring gene uncharacterized LOC102635200 Neighboring gene mitochondrial ribosomal protein S18B Neighboring gene microRNA 1894 Neighboring gene ring-box 1, pseudogene Neighboring gene protein phosphatase 1, regulatory subunit 10 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Transgenic (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein phosphatase 1 binding ISO
Inferred from Sequence Orthology
more info
 
protein phosphatase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
negative regulation of cardiac muscle cell apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of mitotic DNA damage checkpoint ISO
Inferred from Sequence Orthology
more info
 
positive regulation of telomere maintenance ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
PTW/PP1 phosphatase complex IDA
Inferred from Direct Assay
more info
PubMed 
chromatin IDA
Inferred from Direct Assay
more info
PubMed 
nuclear body ISO
Inferred from Sequence Orthology
more info
 
nuclear chromatin ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with nuclear chromosome, telomeric region ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
serine/threonine-protein phosphatase 1 regulatory subunit 10
Names
HLA-C adjacent transcript 53
MHC class I region proline-rich protein CAT53
protein phosphatase I

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163818.1NP_001157290.1  serine/threonine-protein phosphatase 1 regulatory subunit 10

    See identical proteins and their annotated locations for NP_001157290.1

    Status: VALIDATED

    Source sequence(s)
    AW456628, BC052059
    Consensus CDS
    CCDS50098.1
    UniProtKB/Swiss-Prot
    Q80W00
    Related
    ENSMUSP00000084460.6, ENSMUST00000087210.6
    Conserved Domains (2) summary
    pfam00642
    Location:857880
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    cl00146
    Location:102146
    TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme
  2. NM_001357740.1NP_001344669.1  serine/threonine-protein phosphatase 1 regulatory subunit 10

    Status: VALIDATED

    Source sequence(s)
    AJ504718, CR974451
    Conserved Domains (2) summary
    pfam00642
    Location:857880
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    cl00146
    Location:102146
    TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000083.6 Reference GRCm38.p6 C57BL/6J

    Range
    35916512..35932283
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006524617.2XP_006524680.1  serine/threonine-protein phosphatase 1 regulatory subunit 10 isoform X1

    See identical proteins and their annotated locations for XP_006524680.1

    UniProtKB/Swiss-Prot
    Q80W00
    Related
    ENSMUSP00000084461.2, ENSMUST00000087211.8
    Conserved Domains (2) summary
    pfam00642
    Location:857880
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    cl00146
    Location:102146
    TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme
  2. XM_006524619.3XP_006524682.1  serine/threonine-protein phosphatase 1 regulatory subunit 10 isoform X1

    See identical proteins and their annotated locations for XP_006524682.1

    UniProtKB/Swiss-Prot
    Q80W00
    Conserved Domains (2) summary
    pfam00642
    Location:857880
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    cl00146
    Location:102146
    TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme
  3. XM_006524616.3XP_006524679.1  serine/threonine-protein phosphatase 1 regulatory subunit 10 isoform X1

    See identical proteins and their annotated locations for XP_006524679.1

    UniProtKB/Swiss-Prot
    Q80W00
    Conserved Domains (2) summary
    pfam00642
    Location:857880
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    cl00146
    Location:102146
    TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme
  4. XM_030249898.1XP_030105758.1  serine/threonine-protein phosphatase 1 regulatory subunit 10 isoform X1

Reference GRCm38.p6 NOD/MrkTac

Genomic

  1. NT_187027.1 Reference GRCm38.p6 NOD/MrkTac

    Range
    2226590..2241673
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p6 NOD/ShiLtJ

Genomic

  1. NT_187004.1 Reference GRCm38.p6 NOD/ShiLtJ

    Range
    2250212..2265295
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_175934.3: Suppressed sequence

    Description
    NM_175934.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein
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