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RTRAF RNA transcription, translation and transport factor [ Homo sapiens (human) ]

Gene ID: 51637, updated on 5-Sep-2021

Summary

Official Symbol
RTRAFprovided by HGNC
Official Full Name
RNA transcription, translation and transport factorprovided by HGNC
Primary source
HGNC:HGNC:23169
See related
Ensembl:ENSG00000087302 MIM:610858
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CLE; CLE7; hCLE; CGI99; RLLM1; hCLE1; CGI-99; LCRP369; C14orf166
Expression
Ubiquitous expression in testis (RPKM 109.7), fat (RPKM 62.2) and 25 other tissues See more
Orthologs
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Genomic context

See RTRAF in Genome Data Viewer
Location:
14q22.1
Exon count:
8
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (51989546..52010694)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (52456264..52477412)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene G protein subunit gamma 2 Neighboring gene uncharacterized LOC102723604 Neighboring gene uncharacterized LOC105370497 Neighboring gene Sharpr-MPRA regulatory region 5932 Neighboring gene nidogen 2 Neighboring gene uncharacterized LOC105378180 Neighboring gene CAGE-defined high expression enhancer upstream of NID2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Rev rev HIV-1 Rev interacting protein, chromosome 14 open reading frame 166 (C14orf166), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells. The interaction of Rev with C14orf166 is increased by RRE PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables RNA polymerase II complex binding IDA
Inferred from Direct Assay
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in mitotic spindle IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
part_of tRNA-splicing ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of tRNA-splicing ligase complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
RNA transcription, translation and transport factor protein
Names
CLE7 homolog
RLL motif containing 1
UPF0568 protein C14orf166

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016039.3NP_057123.1  RNA transcription, translation and transport factor protein

    See identical proteins and their annotated locations for NP_057123.1

    Status: VALIDATED

    Source sequence(s)
    AF151857, AL358333, BF594675
    Consensus CDS
    CCDS9705.1
    UniProtKB/Swiss-Prot
    Q9Y224
    UniProtKB/TrEMBL
    Q549M8
    Related
    ENSP00000261700.3, ENST00000261700.8
    Conserved Domains (1) summary
    pfam10036
    Location:8243
    RLL; Putative carnitine deficiency-associated protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    51989546..52010694
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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