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CEND1 cell cycle exit and neuronal differentiation 1 [ Homo sapiens (human) ]

Gene ID: 51286, updated on 17-Nov-2018

Summary

Official Symbol
CEND1provided by HGNC
Official Full Name
cell cycle exit and neuronal differentiation 1provided by HGNC
Primary source
HGNC:HGNC:24153
See related
Ensembl:ENSG00000184524 MIM:608213; Vega:OTTHUMG00000133308
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BM88
Summary
The protein encoded by this gene is a neuron-specific protein. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Multiple pseudogenes have been reported for this gene. [provided by RefSeq, Jul 2008]
Expression
Biased expression in brain (RPKM 37.5) and adrenal (RPKM 2.6) See more
Orthologs

Genomic context

See CEND1 in Genome Data Viewer
Location:
11p15.5
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 11 NC_000011.10 (787110..790126, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (787110..790126, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene glutamine amidotransferase like class 1 domain containing 1 Neighboring gene uncharacterized LOC171391 Neighboring gene solute carrier family 25 member 22 Neighboring gene proapoptotic nucleolar protein 1 Neighboring gene p53-induced death domain protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ90066, MGC34326

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
adult walking behavior IEA
Inferred from Electronic Annotation
more info
 
biological_process ND
No biological Data available
more info
 
cerebellar Purkinje cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cerebellar granular layer maturation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of cerebellar granule cell precursor proliferation IEA
Inferred from Electronic Annotation
more info
 
neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
radial glia guided migration of cerebellar granule cell IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with vesicle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
cell cycle exit and neuronal differentiation protein 1
Names
BM88 antigen

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016564.3NP_057648.2  cell cycle exit and neuronal differentiation protein 1

    See identical proteins and their annotated locations for NP_057648.2

    Status: REVIEWED

    Source sequence(s)
    AP006621, DA066200
    Consensus CDS
    CCDS7714.1
    UniProtKB/Swiss-Prot
    Q8N111
    Related
    ENSP00000328336.4, OTTHUMP00000164431, ENST00000330106.4, OTTHUMT00000257105
    Conserved Domains (1) summary
    pfam15677
    Location:1149
    CEND1; Cell cycle exit and neuronal differentiation protein 1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p12 Primary Assembly

    Range
    787110..790126 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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