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CEND1 cell cycle exit and neuronal differentiation 1 [ Homo sapiens (human) ]

Gene ID: 51286, updated on 22-Sep-2022

Summary

Official Symbol
CEND1provided by HGNC
Official Full Name
cell cycle exit and neuronal differentiation 1provided by HGNC
Primary source
HGNC:HGNC:24153
See related
Ensembl:ENSG00000184524 MIM:608213; AllianceGenome:HGNC:24153
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BM88
Summary
The protein encoded by this gene is a neuron-specific protein. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Multiple pseudogenes have been reported for this gene. [provided by RefSeq, Jul 2008]
Expression
Biased expression in brain (RPKM 37.5) and adrenal (RPKM 2.6) See more
Orthologs
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Genomic context

See CEND1 in Genome Data Viewer
Location:
11p15.5
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (787115..790090, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (838549..841523, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (787115..790090, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene glutamine amidotransferase class 1 domain containing 1 Neighboring gene uncharacterized LOC124900301 Neighboring gene GATD1 divergent transcript Neighboring gene solute carrier family 25 member 22 Neighboring gene proapoptotic nucleolar protein 1 Neighboring gene p53-induced death domain protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ90066, MGC34326

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in adult walking behavior IEA
Inferred from Electronic Annotation
more info
 
involved_in biological_process ND
No biological Data available
more info
 
involved_in cerebellar Purkinje cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cerebellar granular layer maturation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in negative regulation of cerebellar granule cell precursor proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in radial glia guided migration of cerebellar granule cell IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with vesicle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
cell cycle exit and neuronal differentiation protein 1
Names
BM88 antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016564.4NP_057648.2  cell cycle exit and neuronal differentiation protein 1

    See identical proteins and their annotated locations for NP_057648.2

    Status: REVIEWED

    Source sequence(s)
    AP006621, DA066200
    Consensus CDS
    CCDS7714.1
    UniProtKB/Swiss-Prot
    Q8N111, Q9NYM6
    Related
    ENSP00000328336.4, ENST00000330106.5
    Conserved Domains (1) summary
    pfam15677
    Location:1149
    CEND1; Cell cycle exit and neuronal differentiation protein 1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    787115..790090 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    838549..841523 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)