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Cend1 cell cycle exit and neuronal differentiation 1 [ Mus musculus (house mouse) ]

Gene ID: 57754, updated on 8-Jan-2023

Summary

Official Symbol
Cend1provided by MGI
Official Full Name
cell cycle exit and neuronal differentiation 1provided by MGI
Primary source
MGI:MGI:1929898
See related
Ensembl:ENSMUSG00000060240 AllianceGenome:MGI:1929898
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BM88; 1500001H12Rik
Summary
Involved in neuron differentiation. Acts upstream of or within adult walking behavior; hindbrain development; and negative regulation of cerebellar granule cell precursor proliferation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to colocalize with mitochondrion and vesicle. Is expressed in central nervous system; peripheral nervous system ganglion; sensory organ; and urethra. Orthologous to human CEND1 (cell cycle exit and neuronal differentiation 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cerebellum adult (RPKM 92.4), cortex adult (RPKM 51.6) and 4 other tissues See more
Orthologs
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Genomic context

See Cend1 in Genome Data Viewer
Location:
7; 7 F5
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (141006359..141009475, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (141426446..141429562, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene RAN guanine nucleotide release factor pseudogene Neighboring gene glutamine amidotransferase like class 1 domain containing 1 Neighboring gene solute carrier family 25 (mitochondrial carrier, glutamate), member 22 Neighboring gene p53 induced death domain protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with mitochondrion ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with vesicle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
cell cycle exit and neuronal differentiation protein 1
Names
BM88 antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360485.1NP_001347414.1  cell cycle exit and neuronal differentiation protein 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC158224, AC163434
    Consensus CDS
    CCDS22012.1
    UniProtKB/Swiss-Prot
    Q9DBA0
    UniProtKB/TrEMBL
    A0A8C6N3J9
    Related
    ENSMUSP00000123334.2, ENSMUST00000137488.2
    Conserved Domains (1) summary
    pfam15677
    Location:1149
    CEND1; Cell cycle exit and neuronal differentiation protein 1
  2. NM_021316.5NP_067291.1  cell cycle exit and neuronal differentiation protein 1

    See identical proteins and their annotated locations for NP_067291.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC158224, AC163434, AK079045
    Consensus CDS
    CCDS22012.1
    UniProtKB/Swiss-Prot
    Q9DBA0, Q9JKC6
    UniProtKB/TrEMBL
    A0A8C6N3J9
    Related
    ENSMUSP00000118591.2, ENSMUST00000124444.2
    Conserved Domains (1) summary
    pfam15677
    Location:1149
    CEND1; Cell cycle exit and neuronal differentiation protein 1

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    141006359..141009475 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)