Format

Send to:

Choose Destination

ZNF593 zinc finger protein 593 [ Homo sapiens (human) ]

Gene ID: 51042, updated on 9-Dec-2018

Summary

Official Symbol
ZNF593provided by HGNC
Official Full Name
zinc finger protein 593provided by HGNC
Primary source
HGNC:HGNC:30943
See related
Ensembl:ENSG00000142684 MIM:616698
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZT86
Expression
Ubiquitous expression in colon (RPKM 5.2), kidney (RPKM 4.4) and 25 other tissues See more
Orthologs

Genomic context

See ZNF593 in Genome Data Viewer
Location:
1p36.11
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 1 NC_000001.11 (26169897..26170873)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (26496388..26497364)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 110 member D Neighboring gene chromosome 1 open reading frame 230 Neighboring gene connector enhancer of kinase suppressor of Ras 1 Neighboring gene cation channel sperm associated 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific NAS
Non-traceable Author Statement
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
ribosomal large subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
zinc ion binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
nucleolus IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
 
preribosome, large subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 593
Names
zinc finger protein T86

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015871.5NP_056955.2  zinc finger protein 593

    See identical proteins and their annotated locations for NP_056955.2

    Status: VALIDATED

    Source sequence(s)
    AI083892, DA124660
    Consensus CDS
    CCDS275.2
    UniProtKB/Swiss-Prot
    O00488
    Related
    ENSP00000363384.5, ENST00000374266.6
    Conserved Domains (1) summary
    cl26385
    Location:1108
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p12 Primary Assembly

    Range
    26169897..26170873
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center