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Zfp593 zinc finger protein 593 [ Mus musculus (house mouse) ]

Gene ID: 68040, updated on 26-Sep-2022


Official Symbol
Zfp593provided by MGI
Official Full Name
zinc finger protein 593provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000028840 AllianceGenome:MGI:1915290
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ZNF593; 3110024A21Rik; E130106C14Rik
Predicted to enable zinc ion binding activity. Predicted to be involved in negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding activity and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleolus and nucleoplasm. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; retina; and submandibular gland primordium. Orthologous to human ZNF593 (zinc finger protein 593). [provided by Alliance of Genome Resources, Apr 2022]
Ubiquitous expression in adrenal adult (RPKM 7.1), ovary adult (RPKM 6.1) and 28 other tissues See more
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Genomic context

See Zfp593 in Genome Data Viewer
4; 4 D2.3
Exon count:
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (133970617..133972902, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (134243306..134245591, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene cation channel, sperm associated 4 Neighboring gene connector enhancer of kinase suppressor of Ras 1 Neighboring gene RIKEN cDNA E130218I03 gene Neighboring gene predicted gene, 30191 Neighboring gene family with sequence similarity 110, member D Neighboring gene predicted gene, 42325

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a




Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
enables preribosome binding ISO
Inferred from Sequence Orthology
more info
enables zinc ion binding ISO
Inferred from Sequence Orthology
more info
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
located_in nucleus IEA
Inferred from Electronic Annotation
more info

General protein information

Preferred Names
zinc finger protein 593
zinc finger protein T86

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024215.2NP_077177.2  zinc finger protein 593

    See identical proteins and their annotated locations for NP_077177.2

    Status: VALIDATED

    Source sequence(s)
    AK005247, AK014081, CO040973
    Consensus CDS
    Q99J54, Q9DB42
    ENSMUSP00000030644.8, ENSMUST00000030644.8
    Conserved Domains (2) summary
    UFD2; U1-like Zn-finger-containing protein [General function prediction only]
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000070.7 Reference GRCm39 C57BL/6J

    133970617..133972902 complement
    GenBank, FASTA, Sequence Viewer (Graphics)