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RRP15 ribosomal RNA processing 15 homolog [ Homo sapiens (human) ]

Gene ID: 51018, updated on 3-May-2020

Summary

Official Symbol
RRP15provided by HGNC
Official Full Name
ribosomal RNA processing 15 homologprovided by HGNC
Primary source
HGNC:HGNC:24255
See related
Ensembl:ENSG00000067533 MIM:611193
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CGI-115; KIAA0507
Summary
This gene encodes a protein that co-purifies with human nucleoli. A similar protein in budding yeast is a component of pre-60S ribosomal particles, and is required for the early maturation steps of the 60S subunit. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in thyroid (RPKM 2.4), fat (RPKM 2.2) and 25 other tissues See more
Orthologs

Genomic context

See RRP15 in Genome Data Viewer
Location:
1q41
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (218285293..218337983)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (218458629..218511325)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene RNA, U1 small nuclear 141, pseudogene Neighboring gene uncharacterized LOC105372923 Neighboring gene ribosomal protein S26 pseudogene 17 Neighboring gene TGFB2 antisense RNA 1 (head to head) Neighboring gene transforming growth factor beta 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0507, MGC22291

Gene Ontology Provided by GOA

Process Evidence Code Pubs
maturation of 5.8S rRNA IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
maturation of LSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
preribosome, large subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
RRP15-like protein
Names
ribosomal RNA-processing protein 15

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016052.4NP_057136.2  RRP15-like protein

    See identical proteins and their annotated locations for NP_057136.2

    Status: REVIEWED

    Source sequence(s)
    AC096638, AW029169, BC020641, BF242786
    Consensus CDS
    CCDS1520.2
    UniProtKB/Swiss-Prot
    Q9Y3B9
    Related
    ENSP00000355899.3, ENST00000366932.4
    Conserved Domains (1) summary
    pfam07890
    Location:102215
    Rrp15p; Rrp15p

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    218285293..218337983
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011509597.3XP_011507899.1  RRP15-like protein isoform X1

    Conserved Domains (1) summary
    pfam07890
    Location:102215
    Rrp15p; Rrp15p
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