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DAB2 DAB adaptor protein 2 [ Bos taurus (domestic cattle) ]

Gene ID: 509221, updated on 17-Aug-2024

Summary

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Official Symbol
DAB2provided by VGNC
Official Full Name
DAB adaptor protein 2provided by VGNC
Primary source
VGNC:VGNC:27865
See related
BGD:BT19326; Ensembl:ENSBTAG00000016152
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See DAB2 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 20 NC_037347.1 (35004200..35064451)

Chromosome 20 - NC_037347.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC112443037 Neighboring gene complement C9 Neighboring gene FYN binding protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037347.1 Chromosome 20 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Altered expression of inflammation-associated genes in oviductal cells following follicular fluid exposure: implications for ovarian carcinogenesis. Lau A, et al. Exp Biol Med (Maywood), 2014 Jan. PMID 24186266
  2. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
  3. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in receptor-mediated endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
disabled homolog 2
Names
DAB2, clathrin adaptor protein
disabled homolog 2, mitogen-responsive phosphoprotein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001193246.2 → NP_001180175.1  disabled homolog 2

    See identical proteins and their annotated locations for NP_001180175.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000020
    UniProtKB/TrEMBL
    F1N371
    Related
    ENSBTAP00000021501.5, ENSBTAT00000021501.7
    Conserved Domains (2) summary
    cd01215
    Location:36 → 171
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    cl26464
    Location:394 → 611
    Atrophin-1; Atrophin-1 family

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037347.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    35004200..35064451
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059878690.1 → XP_059734673.1  disabled homolog 2 isoform X1

    UniProtKB/TrEMBL
    F1N371

  2. XM_005221592.3 → XP_005221649.1  disabled homolog 2 isoform X1

    See identical proteins and their annotated locations for XP_005221649.1

    UniProtKB/TrEMBL
    F1N371
    Conserved Domains (2) summary
    cd01215
    Location:36 → 171
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    cl26464
    Location:394 → 611
    Atrophin-1; Atrophin-1 family

  3. XM_015459082.3 → XP_015314568.1  disabled homolog 2 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1LKF9, A0A3Q1MXS6
    Related
    ENSBTAP00000060061.1, ENSBTAT00000078306.2
    Conserved Domains (2) summary
    cd01215
    Location:36 → 171
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    cl26464
    Location:221 → 393
    Atrophin-1; Atrophin-1 family

  4. XM_010816799.3 → XP_010815101.1  disabled homolog 2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LSX5
    Related
    ENSBTAP00000060131.1, ENSBTAT00000079720.2
    Conserved Domains (2) summary
    cd01215
    Location:36 → 171
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    cl26464
    Location:373 → 590
    Atrophin-1; Atrophin-1 family
Nucleotide Protein Strain
Heading Accession and Version

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