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ARHGAP42 Rho GTPase activating protein 42 [ Bos taurus (domestic cattle) ]

Gene ID: 508009, updated on 17-Aug-2024

Summary

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Official Symbol
ARHGAP42provided by VGNC
Official Full Name
Rho GTPase activating protein 42provided by VGNC
Primary source
VGNC:VGNC:26096
See related
Ensembl:ENSBTAG00000004423
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 15
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (8003637..8351659, complement)

Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene adenosylhomocysteinase-like Neighboring gene progesterone receptor Neighboring gene ubiquitin-related modifier 1-like Neighboring gene uncharacterized LOC112441562 Neighboring gene 60S ribosomal protein L6 pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
  2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • FLJ32810

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 10-like; rho GTPase-activating protein 42

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    8003637..8351659 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003586932.6 → XP_003586980.1  rho GTPase-activating protein 42 isoform X1

    See identical proteins and their annotated locations for XP_003586980.1

    UniProtKB/TrEMBL
    A0A3Q1LL23, A0A3Q1MT43
    Related
    ENSBTAP00000057783.1, ENSBTAT00000077406.2
    Conserved Domains (5) summary
    cd07634
    Location:19 → 225
    BAR_GAP10-like; The Bin/Amphiphysin/Rvs (BAR) domain of Rho GTPase activating protein 10-like
    cd12066
    Location:820 → 874
    SH3_GRAF3; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase 3
    cd04374
    Location:369 → 567
    RhoGAP_Graf; RhoGAP_Graf: GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences ...
    cd01249
    Location:267 → 376
    BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
    pfam00169
    Location:267 → 369
    PH; PH domain

  2. XM_059875064.1 → XP_059731047.1  rho GTPase-activating protein 42 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1MIB3, A0AAA9S632
    Related
    ENSBTAP00000071001.1, ENSBTAT00000081166.2

  3. XM_059875065.1 → XP_059731048.1  rho GTPase-activating protein 42 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1LFB4, A0AAA9S632

  4. XM_024975717.2 → XP_024831485.1  rho GTPase-activating protein 42 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1LFB4, A0AAA9S632
    Related
    ENSBTAP00000056823.1, ENSBTAT00000078047.2
    Conserved Domains (4) summary
    cd12066
    Location:766 → 820
    SH3_GRAF3; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase 3
    cd04374
    Location:315 → 513
    RhoGAP_Graf; RhoGAP_Graf: GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences ...
    cd01249
    Location:213 → 322
    BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
    cl12013
    Location:1 → 171
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001075343.1: Suppressed sequence

    Description
    NM_001075343.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: ARHGAP42 (GeneID:143872).
Nucleotide Protein Strain
Heading Accession and Version

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