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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001163430.2 → NP_001156902.1 NAD-dependent protein deacetylase sirtuin-6 isoform 2
See identical proteins and their annotated locations for NP_001156902.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) differs in the UTRs and 5' coding region and initiates translation at a downstream start codon, compared to variant 1. The resulting isoform (2) has a shorter N-terminus compared to isoform 1. Variants 2 and 4 both encode the same isoform (2).
- Source sequence(s)
-
AC153919
- Consensus CDS
-
CCDS48645.1
- UniProtKB/TrEMBL
-
Q3UKP1
- Related
- ENSMUSP00000113953.2, ENSMUST00000119324.8
- Conserved Domains (1) summary
-
- cd01410
Location:5 → 217
- SIRT7; Eukaryotic and prokaryotic group (class4) which includes human sirtuin SIRT6, SIRT7, and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein ...
-
NM_001378944.1 → NP_001365873.1 NAD-dependent protein deacetylase sirtuin-6 isoform 1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3), as well as variant 1, encodes isoform 1.
- Source sequence(s)
-
AC153919
- Conserved Domains (1) summary
-
- cd01410
Location:45 → 257
- SIRT7; Eukaryotic and prokaryotic group (class4) which includes human sirtuin SIRT6, SIRT7, and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein ...
-
NM_001378945.1 → NP_001365874.1 NAD-dependent protein deacetylase sirtuin-6 isoform 2
Status: VALIDATED
- Description
- Transcript Variant: This variant (4), as well as variant 2, encodes isoform 2.
- Source sequence(s)
-
AC153919
- Conserved Domains (1) summary
-
- cd01410
Location:5 → 217
- SIRT7; Eukaryotic and prokaryotic group (class4) which includes human sirtuin SIRT6, SIRT7, and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein ...
-
NM_181586.4 → NP_853617.1 NAD-dependent protein deacetylase sirtuin-6 isoform 1
See identical proteins and their annotated locations for NP_853617.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1). Variants 1 and 3 both encode the same isoform (1).
- Source sequence(s)
-
AC153919
- Consensus CDS
-
CCDS24066.1
- UniProtKB/Swiss-Prot
-
P59941
- Related
- ENSMUSP00000048971.9, ENSMUST00000042923.9
- Conserved Domains (1) summary
-
- cd01410
Location:45 → 257
- SIRT7; Eukaryotic and prokaryotic group (class4) which includes human sirtuin SIRT6, SIRT7, and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein ...
RNA
-
NR_166193.1 RNA Sequence
Status: VALIDATED
- Source sequence(s)
-
AC153919
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000076.7 Reference GRCm39 C57BL/6J
- Range
-
81457621..81463631 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011243507.4 → XP_011241809.1 NAD-dependent protein deacetylase sirtuin-6 isoform X1
- Conserved Domains (1) summary
-
- cl00195
Location:101 → 261
- SIR2; SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, ...