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OMG oligodendrocyte myelin glycoprotein [ Homo sapiens (human) ]

Gene ID: 4974, updated on 6-May-2021

Summary

Official Symbol
OMGprovided by HGNC
Official Full Name
oligodendrocyte myelin glycoproteinprovided by HGNC
Primary source
HGNC:HGNC:8135
See related
Ensembl:ENSG00000126861 MIM:164345
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OMGP
Expression
Restricted expression toward brain (RPKM 57.3) See more
Orthologs
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Genomic context

See OMG in Genome Data Viewer
Location:
17q11.2
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210226 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (31294647..31297239, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (29621665..29624257, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene neurofibromin 1 Neighboring gene NF1 intron 8 Alu-mediated recombination region Neighboring gene uncharacterized LOC101927057 Neighboring gene ecotropic viral integration site 2B Neighboring gene ecotropic viral integration site 2A

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of axonogenesis TAS
Traceable Author Statement
more info
 
involved_in neuron projection regeneration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
oligodendrocyte-myelin glycoprotein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_002544.5NP_002535.3  oligodendrocyte-myelin glycoprotein precursor

    See identical proteins and their annotated locations for NP_002535.3

    Status: VALIDATED

    Source sequence(s)
    AC134669, BC018050, DA206834
    Consensus CDS
    CCDS11265.1
    UniProtKB/Swiss-Prot
    P23515
    Related
    ENSP00000247271.4, ENST00000247271.5
    Conserved Domains (3) summary
    smart00013
    Location:2559
    LRRNT; Leucine rich repeat N-terminal domain
    sd00033
    Location:3756
    LRR_RI; leucine-rich repeat [structural motif]
    cl26018
    Location:45219
    NEL; C-terminal novel E3 ligase, LRR-interacting

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210226

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    31294647..31297239 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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